高血压病虚实辨证与血浆ETTXB_2等指标的关系  

Syndrome differentiation of hypertention and plasma ET and TXB2

作　　者：罗伟[1] 李保东[1] 冯小平 李桂金[1] 张新[1] 刘洁 

机构地区：[1]徐州市第四人民医院 [2]徐州市心血管病研究所

出　　处：《辽宁中医杂志》1999年第5期206-207,共2页Liaoning Journal of Traditional Chinese Medicine

摘　　要：探讨高血压病虚实辨证与血浆ＥＴ、ＴＸＢ２、６－Ｋ－ＰＧＦ１α水平的关系。用放免法测定７１例高血压病患者血浆ＥＴ、ＴＸＢ２、６－Ｋ－ＰＧＦ１α浓度，并与２０名健康者对照。结果，患者组ＥＴ、ＴＸＢ２值均高于健康组（Ｐ＜０．０５～０．０１），实证组高于虚证组（Ｐ＜０．０１）；虚证组６－Ｋ－ＰＧＦ１α低于实证组和健康组（Ｐ＜０．０１），实证组与健康组无显著差异（Ｐ＞０．０５）。结论，高血压病实证以ＥＴ、ＴＸＢ２显著增高为特征，虚证以６－Ｋ－ＰＧＦ１α降低为显著特征。提示上述指标可能是高血压病虚实辨证分型的客观物质基础之一。To investigate the relationship of plasma ET,TXB 2,6-K-PGF 1 α to excessive and deficienly syndrome differentiation of traditional Chinese medicine in hypertension.Methods:The level of plasma,ET,TXB 2,6-K-PGF 1α was measured by RIA in 71 cases of hypertensive patients and 20 cases of normal control humen.Results:The level of plasma ET and TXB 2 was higher than that of normal control group(P<0.05￣0.01),but the level in excessive syndrome group higher than in deficiency syndrome(P<0.01);The level of plasma 6-K-PGF 1α was showed that deficiency syndrome group ws lower than exerssive syndrome group and normal control group(P<0.01),but no significant difference between excessive syndrome group and normal group(P>0.05).Conclusion:The level of ET and TXB 2 was significantly increased in patients with excessive syndrome.The level of 6-K-PGF 1α was significantly decreased in patients with deficiency syndrome.The results suggested that ET,TXB 2 and 6-K-PGF 1α are one of the objective material basis for typing excessive and dificiency sydndrome differentiation.

关 键 词：高血压 ET TXB2 虚实辨证 

分 类 号：R259.441[医药卫生—中西医结合]