人和常用实验动物正常涎腺中肌上皮细胞定量组织学研究  

An Immunohistochemical and Morphometric Study of Myoepithelial Cells in Salivary Glands of Human and Experimental Animals

作　　者：马文波[1] 何志秀[1] 卢勇[1] 刘吉余[1] 蔡益新[1] 

机构地区：[1]华西医科大学口腔医学院

出　　处：《华西口腔医学杂志》1999年第2期105-107,共3页West China Journal of Stomatology

基　　金：卫生部科学基金

摘　　要：目的：了解人与不同实验动物涎腺中肌上皮细胞的差异。方法：用ＨＨＦ３５对人和动物涎腺进行免疫组织化学染色，用计算机图像分析系统测量肌上皮细胞的平均体积比并进行比较。结果：人和动物涎腺中肌上皮细胞的平均体积比存在不同程度的差异。除啮齿类动物外，人和其它动物粘液腺中肌上皮细胞的平均体积比高于浆液腺中者。结论：涎腺肌上皮细胞的平均体积比与动物种类和涎腺分泌物性能有关。Objective:To investigate whether differences exist between myoepithelial cells of human beings and experimental animals.Methods: Myoepithelial cells(MeCs) of 8 kinds of experimental animals were studied immunohistochemically using muscle acting specific monoclonal antibody HHF35 and morphometrically using image analysis.Results: There were differences in mean proportional volumes of MeCs between human beings and experimental animals. The mean proportional volumes of mucous acini were more than those of serous acini except salivary glands of rodents.Conclusion: The mean proportional volume of MeCs in salivary glands associates with animal species and secretion of salivary glands.

关 键 词：实验动物 肌上皮细胞 免疫组织化学 涎腺 

分 类 号：R333.1[医药卫生—人体生理学]