固相萃取-液相色谱-离子阱二级质谱法同时测定饮用水中多种痕量有机污染物  

Simultaneous Determination of 15 Kinds of Trace Organic Pollutants in Drinking Water by Solid-phase Extraction-Liquid Chromatography-Ion Trap Mass /Mass Spectrometry

作　　者：颜流水[1] 江鑫[1] 曹群[1] 黄燕[1] 

机构地区：[1]南昌航空大学环境与化学工程学院,南昌330063

出　　处：《化学通报》2010年第9期850-853,共4页Chemistry

基　　金：国家自然科学基金项目(20765003)资助

摘　　要：建立了高效液相色谱-离子阱二级质谱法同时测定饮用水中内分泌干扰物、农药残留和丙烯酰胺等15种痕量有机污染物的方法。250mL水样先用C18固相萃取柱富集,经梯度洗脱液相色谱分离,采用时间分段的方法确定各组分质谱检测条件,利用离子阱二级质谱进行测定。所检测的15种有机污染物定量线性关系良好,相关系数为0.9975～0.9998,检测限在0.2～20ng/L之间。在低、中、高3个不同加标水平下,实际水样的加标回收率为75.1%～99.5%,相对标准偏差为4.6%～12.3%。该方法成功用于5种不同来源饮用水样的检测,获得了满意结果。A high performance liquid chromatography-ion trap mass /mass spectrometric method had been developed for the simultaneous determination of 15 trace organic pollutants including endocrine disrupting compounds,pesticide residues and acrylamide in drinking water.The procedure includes an off-line solid-phase extraction of 250mL water samples with a C18 cartridge,followed by liquid chromatographic separation with gradient elution,and then detection by ion trap mass /mass spectrometry in consecutive time segments corresponding to the elution window of the different analytes.Good linear range was obtained for all analytes with the correlation coefficients of 0.9975 ～ 0.9998,and the detection limits were 0.2 ～ 20ng /L.The average recoveries of 15 analytes in spiked tap water samples with low,medium and high levels ranged from 75.1% ～ 99.5%,and the relative standard deviations were between 4.6% ～ 12.3% 。 The presented method has been applied to the analysis of 5 kinds of drinking water samples with satisfactory results.

关 键 词：液质联用离子阱二级质谱 内分泌干扰物 饮用水 多残留分析 同时测定 

分 类 号：R123.1[医药卫生—环境卫生学]