急性冠脉综合征46例血尿酸与尿微量蛋白的检测及相互关系的研究  

Clinical study of relationship between uric acid and urinary microprotein in patients with acute coronary syndrome

作　　者：朱平[1] 冯青俐[1] 

机构地区：[1]河南省洛阳市中心医院急诊科,洛阳471009

出　　处：《陕西医学杂志》2010年第9期1240-1242,共3页Shaanxi Medical Journal

摘　　要：目的:探讨急性冠脉综合征(ACS)患者血清尿酸(UA)与尿微量白蛋白(MAU)的关系。方法:对21例急性心肌梗死(AMI)患者,25例不稳定心绞痛(UAP)患者及20例健康人血清UA水平及MAU水平进行检测,分析冠状动脉病变情况。结果:1血清UA,MAU在AMI组及UAP组高于对照组。2ACS组冠状动脉狭窄程度积分与血UA,MAU水平呈正相关。ACS组血UA与MAU水平呈正相关。结论:ACS患者UA升高可能参与肾功能损伤。Objective：To explore the correlation and its significance of uric acid and urinary microprotein of patients with acute coronary syndrome（ACS）.Methods：Uric acid（UA）and urinary microproteinsis（MAU） were measured in forty-six patients with acute coronary syndrome（ACS group） and twenty patients with control subjects（control group）,and coronary artery lesions were analyzed.Results：① Uric acid levels and urinary microprotein were significantly higher in patients with ACS than in control group.② The level of uric acid and urinary microproteinsis was correlated with culprit coronary artery lesion in ACS;Uric acid level was positively correlated with urinary microprotein level in ACS.Conclusion：The increase of uric acid in patients with ACS can injury renal.

关 键 词：心肌梗塞/病因学 心绞痛 不稳定型/病因学 尿酸/代谢 蛋白/尿 蛋白/代谢 

分 类 号：R542.22[医药卫生—心血管疾病]