肥胖及血脂异常与2型糖尿病关系  

Relationship between obesity,dyslipidemia and type 2 diabetes

作　　者：张阳丹[1] 唐晓君[1] 李革[1] 张名均 滕小春[3] 陈春全[3] 李建华[4] 

机构地区：[1]重庆医科大学流行病学教研室,重庆401331 [2]重庆市九龙坡区第一人民医院检验科 [3]重钢总医院 [4]重庆医科大学

出　　处：《中国公共卫生》2010年第9期1112-1113,共2页Chinese Journal of Public Health

基　　金：重庆市教委自科项目(KJ070313)

摘　　要：目的探讨肥胖及血脂异常与2型糖尿病的关系。方法采用病例对照研究方法,选取重庆市3所医院的糖尿病门诊和住院初诊患者及其他疾病和门诊健康体检者396例作为调查对象;其中糖尿病病例组184例,对照组212人。对调查对象进行问卷调查、体格检查和生化指标等实验室检测。结果病例组体质指数(BMI)、腰臀比(WHR)、血清总胆固醇(TC)、甘油三酯(TG)均高于对照组,差异均有统计学意义(P<0.05);病例组超重及肥胖检出率(64.67%)、腹型肥胖检出率(77.17%)、高TC检出率(27.17%)、高TG检出率(50.00%)均高于对照组(45.28%,64.15%,14.15%,35.38%),差异均有统计学意义;经多因素非条件Logistic回归分析显示,高胆固醇、超重及肥胖是糖尿病的主要危险因素。结论肥胖和血脂异常与2型糖尿病相关,控制体重、合理膳食是预防2型糖尿病发生的重要措施。Objective To study the relationship between obesity,dyslipidemia and type 2 diabetes.Methods A case-control study among 184 type 2 diabetes patients from 3 hospitals and 212 normal health examinees was conducted in Chongqing city during the period of Oct,2008 to Feb,2009.Results The body mass index（BMI）,waist-hip ratio（WHR）,serum total cholesterol（TC）,and triglyceride（TG）of the case group were higher than those of the control group.And the t test demonstrated that the differences were statistically significant.The overweight and obesity rates（64.67%）,the detection rates of high TC（27.17%）and high TG（50.00%）of the case group were higher than those of the control group with significant differences.The multi-factor non-conditional logistic regression analysis showed that hypercholesterolemia,overweight and obesity were major risk factors for type 2 diabetes.Conclusion Obesity and dyslipidemia are related to the occurrence of type 2 diabetes.Controlling weight and a reasonable diet are important measures to prevent type 2 diabetes.

关 键 词：肥胖 血脂异常 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]