天目当归和大叶当归化学成分研究  

Studies on the Chemical Constituents in Roots of Angelica tianmuensis and A. megaphylla

作　　者：宋萍萍[1] 徐增莱[1] 王年鹤[1] 

机构地区：[1]江苏省中科院植物研究所/南京中山植物园,江苏南京210014

出　　处：《中药材》2010年第8期1249-1251,共3页Journal of Chinese Medicinal Materials

基　　金：国家自然科学基金资助项目(30270097)

摘　　要：目的:研究天目当归和大叶当归的化学成分。方法:采用硅胶柱层析进行分离纯化,根据理化性质和现代波谱技术进行结构鉴定。结果:从天目当归中鉴定得到1个倍半萜类化合物ligustilone(Ⅰ)和两个色原酮类化合物5-methoxyhamaudol(Ⅱ)、cimifugin(Ⅲ);从大叶当归中鉴定得到1个倍半萜类化合物ligustilone(Ⅳ)及1个简单香豆素当归醇(Ⅴ)。结论:所有化合物均为首次从此两种植物中分离得到;化合物Ⅳ为首次从当归属植物中分离得到。Objective：To study the chemical constituents in roots of Angelica tianmuensis and A.megaphylla.Methods： Compounds were isolated by column chromatography with silica gel,their structures were identified by spectral analysis.Results： Another three compounds（ligustilone,5-methoxyhamaudol,cimifugin） were obtained from the roots of Angelica tianmuensis,and another two compounds（ligustilone,angelol） were obtained from the roots of A.megaphylla.Conclusion： All the compounds are isolated in these two plants for the first time,and ligustilone is first found from Angelica L..

关 键 词：天目当归 大叶当归 倍半萜 色原酮 香豆素 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]