安徽某监狱一起甲型H1N1流感暴发疫情流行病学调查  

Epidemiological investigation of influenza A (H1N1) outbreak in a prison of Anhui Province

作　　者：何益新[1,2] 吴家兵[3] 王勇[1] 方益荣 孟云[1] 黄永[1] 赵武[1] 汪道发[1] 盛维立[1] 王建军[3] 

机构地区：[1]铜陵市疾病预防控制中心,安徽铜陵244000 [2]铜陵市医学科学研究所,安徽铜陵244000 [3]安徽省疾病预防控制中心,安徽合肥230061 [4]中国现场流行病学培训项目,北京100050

出　　处：《中华疾病控制杂志》2010年第8期705-707,共3页Chinese Journal of Disease Control & Prevention

摘　　要：目的明确甲型H1N1流感病例的来源,探索病例间传播方式,总结防控工作的经验和教训。方法采集流感样病例的咽拭子,采用RT-PCR、Real-timePCR法进行核酸检测。采用现场流行病学调查方法,开展病例诊断、疫情调查和控制工作。结果此起疫情累计发生流感样病例326人,罹患率为17.9%,实验室确诊甲型H1N1病例31人,所有病例经治疗后均痊愈。结论此起疫情为监狱甲型H1N1流感暴发,经采取流行病学调查、停工、隔离治疗、预防服药、个人防护、通风消毒、健康教育等综合措施,疫情得到有效控制。Objective To identify the source of influenza A（H1N1） infections,determine the transmission pattern among patients,and summarize the experience derived from the prevention and control work. Methods Throat swab of influenza-like illness （ILI） cases was collected and DNA of flu virus was determined by RT-PCR and Real-time PCR test. Epidemiological investigation,clinical examination,serological tests,RT-PCR and Real-time PCR test for influenza A （H1N1） cases were used to analyze and diagnose,and proposed control measures. Case diagnosis,epidemiological investigation and control measures were performed based on the results of on-site epidemiological investigation. Results 326 ILI cases were screened and 31 cases were confirmed with influenza A （H1N1）,and the attack rate of ILI case was 17.9%. All patiens were cured. Conclusions Outbreak of influenza A （H1N1） in a prison was confirmed. Using epidemiological investigation,suspended work,isolation and treatment,preventive medicine,personal protection,ventilation,disinfection and health education,the epidemic was effectively controlled.

关 键 词：流感病毒A型 H1N1亚型 流行病学研究 疾病暴发流行 

分 类 号：R181.81[医药卫生—流行病学] R511.7[医药卫生—公共卫生与预防医学]