止遗合剂对水负荷肾阳虚大鼠排尿次数及排尿量的影响  

Experimental Study of Influences Upon Times of Urine Excreted and Amount of Urine Excreted of Water Load Kidney-Yang Deficiency Model in Rats for Zhiyi Heji

作　　者：凌科[1] 张建民[1] 关晶 解志飞 

机构地区：[1]首都儿科研究所附属儿童医院,北京100020 [2]北京首儿药厂,北京101304

出　　处：《中国实验方剂学杂志》2010年第11期184-186,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:通过动物试验观察止遗合剂对小儿遗尿的治疗作用。方法:用氢化可的松造成大鼠水负荷肾阳虚模型,观察止遗合剂对大鼠的排尿量及排尿次数的影响。结果:止遗合剂可显著减少水负荷肾阳虚大鼠各个时间段的排尿量及排尿次数,以及减少观察期间总排尿次数及总排尿量。结论:止遗合剂能明显减少水负荷肾阳虚大鼠排尿次数及排尿量。Objective ：To do the animal experiment to observe the therapeutic effect of Zhiyi Heji to children’s enuresis.Method：The water load Kidney Yang Deficiency model in rats was made by using hydrocortisone,then observing the influences upon the times of urine excreted and the amount of urine excreted caused by the Zhiyi Heji.Result：The Zhiyi Heji could obviously reduce the times of urine excreted and the amount of urine excreted in any time period and reduce the total times of urine excreted and the total amount of urine excreted in the all observation period of the water load Kidney Yang Deficiency model in rats.Conclusion：The Zhiyi Heji have a good effect to reduce the times of urine excreted and the amount of urine excreted of the water load Kidney-Yang Deficiency model in rats

关 键 词：止遗合剂 排尿量 排尿次数 

分 类 号：R285.5[医药卫生—中药学]