瘤型麻风病周围神经损害及病理特征  

Lepromatous leprosy with peripheral nerve damage and pathological features

作　　者：田淑芬[1] 张亮 陈红群[1] 王毅 

机构地区：[1]贵阳医学院附属医院神经内科,贵州贵阳550004 [2]商丘市第四人民医院神经内科,河南商丘476000 [3]贵阳市第五人民医院,贵州贵阳550004

出　　处：《中风与神经疾病杂志》2010年第7期612-614,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨麻风病周围神经损害的临床表现及病理特征。方法分析1例麻风病的临床资料,行神经电生理、神经超声及病理检查,并对相关文献报道进行综述,研究麻风病的流行特征。结果该例患者神经损害主要累及双侧尺神经、腓总神经等。皮肤损害表现为反复的皮损,疤痕,皮肤病理见泡沫细胞组成的肉芽肿。结论麻风病以周围神经及皮肤损害为主,且有地区分布及年龄分布特点,致残率高,传染源仍然存在,因此应加强麻风病的防治工作。Objective To explore the clinical manifestations of peripheral nerve damage and pathological features of leprosy. Methods The clinical materials of a case of leprosy by conducting nerve electrophysiology and nerve ultrasound and pathology examination were investigated,and the related literaturesof pathological features of leprosy were reviewed. Results The nerve damage of the patient mainly focused on bilateral ulnar and peroneal nerve. Clinical manifestation of skin damage was repeated lesions and scar. Foam cells could be seen in pathology examination of granulomas structure. Conclusion Leprosy mostly involves peripheral nerve and skin damage with the characteristics of regional and age distribution. Due to its high mutilation rate and the existence of infection sources,the prevention work of the disease should be strengthened.

关 键 词：麻风病 周围神经损害 病理 

分 类 号：R755[医药卫生—皮肤病学与性病学] R741[医药卫生—临床医学]