孕早期精神受刺激对出生儿单纯性先心病发病的影响  

The Effect of Mental stress During Early Pregnancy on Congenital Heart Disease(CHD) Occurrence in the Offspring.

作　　者：张泽峰[1,2] 李竹[1,2] 季成叶 赵平[1,2] 洪世欣 李万镇[1,2] 马郁文 

机构地区：[1]北京医科大学中国妇婴保健中心 [2]北京医科大学第一医院

出　　处：《中国公共卫生》1999年第4期307-308,共2页Chinese Journal of Public Health

摘　　要：利用浙江省１３个市县０～２岁儿童先心病普查发现的单纯型先心病病例，采用１∶１配比病例对照研究，调查了３５１对先心病患儿和正常对照的父母孕期前后有关暴露情况。单因素及条件Ｌｏｇｉｓｔｉｃ回归结果显示，母亲孕早期精神受刺激可能增加先心病发病危险。结果提示：为减少先心病发病危险，孕早期应合理调整自己的心理状态，保持心情愉快。The cause of Congenital Heart Disease(CHD) remains unknown.To test the effect of maternal mental stress during early pregnancy on the occurrence of CHD in the offspring,351 pairs of matched cases and controls were studid.Data were derived from CHD general investigation of children aged 0～2 years in ZheJiang Province.The results showed that maternal mental stress during early pregnancy may increase the occurrence risk of CHD in the offspring,the odds ratio and the 95% confidence interval are 9 43 and 2 534～61 88,respectively.To lower the risk of CHD occurrence,it's improtant for newly married women to have a happy mood during early pregnacy.

关 键 词：先天性心脏病 精神刺激 配比病例对照研究 

分 类 号：R541.102[医药卫生—心血管疾病]