格拉司琼预防小儿腹腔镜手术后恶心呕吐  

Granisetron on preventing postoperative nausea and vomiting after laparoscopic surgery in children

作　　者：刘才堂[1] 陈剑[1] 刘江洪[1] 

机构地区：[1]中山大学附属东华医院麻醉科,广东东莞523110

出　　处：《临床医学》2010年第7期26-27,共2页Clinical Medicine

摘　　要：目的观察格拉司琼预防全麻下小儿腹腔镜手术后恶心呕吐的临床效果。方法选择80例ASAⅠ～Ⅱ级行择期全麻下腹腔镜手术的患儿,年龄2～10岁,随机分为两组,每组40例。对照组(C组)给予生理盐水5 ml;格拉司琼组(G组)给予格拉司琼40μg/kg,两组均于手术结束时静脉注射,观察24 h内患儿发生恶心呕吐的次数,计算呕吐率。结果术后恶心呕吐发生率对照组(C组)明显高于格拉司琼组(G组),差异有统计学意义(P<0.01)。结论格拉司琼能有效减少小儿腹腔镜手术后的恶心呕吐。Objective To observe the efficacy of prophylactic use of granisetron（Gra） on preventing postoperative nausea and vomiting after laparoscope surgery in children.Methods Eighty ASAⅠ-Ⅱ children（aged 2～10 years） requiring laparoscopic surgery under general anesthesia were randomly divided into two groups,each of group included 40 children.Group saline（C）were given saline 5 ml,group Gra（G）were given Gra 40 μg/kg were respectively injected intravenously after laparoscope surgery.Results The incidence of PONV decreased significantly in group Gra than that in group C（P0.01）.Conclusion It is effective on prophylactic use of Gra on preventing PONV after laparoscopic surgery in children.

关 键 词：格拉司琼 腹腔镜 术后恶心呕吐 儿童 

分 类 号：R726.1[医药卫生—儿科]