381例妊娠期糖尿病血糖管理与母婴妊娠结局的临床分析  

The influence of pregnant outcomes of 381 cases with GDM on systemic management

作　　者：张跃先[1] 刘云[1] 任利容[1] 

机构地区：[1]深圳市宝安区妇幼保健院产科,广东深圳518101

出　　处：《中国优生与遗传杂志》2010年第9期59-60,21,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨妊娠期糖尿病孕妇系统管理对母婴妊娠结局的影响。方法收集我院2008年1月～2009年12月诊断的妊娠期糖尿病病例381例,分为系统管理组241例和未管理组140例。比较两组病例妊娠并发症及围生儿结局。结果妊娠期糖尿病未管理组子痫前期、羊水过多、早产的发生率较系统管理组明显升高(P<0.05);巨大儿、新生儿高胆红素血症、、新生儿低血糖、心肌病变(包括先天性心脏病)、新生儿呼吸窘迫综合征(NRDS)及胎粪吸入综合征(MAS)的发生率亦明显高于系统管理组(P<0.01),而新生儿窒息率的差异无显著性意义(P>0.05)。结论妊娠期糖尿病与妊娠并发症密切相关,未系统管理及血糖未控制者围生儿结局不良,应加强对妊娠期糖尿病孕妇的孕期管理。Objective：To investigate the effects of systemic management on pregnant women with gestational diabetes mellitus to maternal and neonatal pregnancy outcomes.Methods：Retrospective analysis was performed.381 cases with gestational diabetes mellitus from January 2008 to December 2009 in our hospital were divided into two groups.the intervention group of 241 cases with systemic management,and the control group of 140 cases without systemic management,which we compare the maternal complications,outcomes of pregnancy and the prenatal conditions between the two groups.Results：The rates of pre-eclampsia,polyhydramnios,premature delivery,ketoacidosis,fetal growth restriction,premature rupture of membrane were obvious lower in intervention group than those in the control group（P 0.05） ;The rates of fetal macrosomia,neonatal hyperbilirubinemia,Neonatal hypoglycemia,cardiomyopathy（include congenital cardiac disease）,neonatal respiratory distress syndrome,meconium aspiration syndrome were lower in intervention group than those in the control group（P 0.05）.The difference of neonatal distress between the two groups were not significance（P 0.05）.Conclusion：Gestational diabetes mellitus is closely related to the complications of pregnancy,GDM without systemic management have bad outcomes of maternal and neonatal.Systemic management on GDM can reduce the complications of maternal and neonatal.

关 键 词：妊娠期糖尿病 管理 妊娠并发症 围生儿结局 

分 类 号：R714.25[医药卫生—妇产科学]