血必净治疗产科高凝状态的临床观察  

Study the Treatment Effects to Coagulation Disorders of Traditional Chinese Medicine Xuebijing Injection in Patients

作　　者：孙桢[1] 裘谨[1] 

机构地区：[1]天津中心妇产科医院产科,天津300100

出　　处：《中国医药导刊》2010年第8期1365-1366,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨中药血必净注射液对重度子痫前期的患者凝血功能障碍的疗效及pre-DIC的防治作用。方法:回顾我院近2年住院分娩的60例重度子痫前期患者。对照组30例给予常规综合治疗,治疗组30例患者在对照组同样治疗的基础上以血必净注射液替代常规治疗中的葛根素(剖宫产术后应用),在治疗前及治疗后3天两组患者检测的血细胞压积、D二聚体、纤维蛋白原(FIB)水平变化,统计两组pre-DIC的发病率。结果:治疗3天后,治疗组患者的血细胞压积、D二聚体明显下降,两组间差异有统计学意义(P<0.01)。治疗组患者pre-DIC发病率(5.17%)明显低于对照组(15.31%),差异有统计学意义(P<0.05)。结论:血必净注射液对重度子痫前期患者的凝血功能有治疗保护作用,可显著降低pre-DIC的发病率。Objective：To study the treatment effects to coagulation disorders of traditional Chinese medicine Xuebijing injection in patients with severe preeclampsia and preventive effect of pre-DIC.Metbods：60 patients with severe preeclampsia who were hospitalized for delivery in recent two years were reviewed. Control group with 30 cases were given routine treatment; treatment group,also with 30 cases,on the basis of the same treatment with control group,were given Xuebijing injection replace of conventional treatment puerarin （used after Cesarean section）. Before treatment and 3 days after treatment,patients were detected for hematocrit,D dimer, fibrinogen（FIB） levels,and the incidence of pre-DIC in the two groups was calculated. Results：3 days after treatment,ematocrit,and D dimer of the treatment group were decreased. There was significant difference between the two groups（P〈0.01） The incidence of pre-DIC of treatment group was 5.17%,which was significantly lower than the control group 15.31%. There was significant difference（P〈O, O5）.Conclusions：Xuebijing injection has Protective and therapeutic effects to coagulation function in patients with severe pre-eclampsia,and can significantly reduce the incidence of pre-DIC.

关 键 词：重度子痫前期 血必净注射液 凝血功能障碍 

分 类 号：R714.2[医药卫生—妇产科学]