Wittig反应合成α,β-不饱和酯后处理方法的改进  

An improvement to the work-up method for Wittig reaction Synthesis ofα,β-unsaturated ester

作　　者：李小东[1] 巨婷婷[1] 王小龙[1] 

机构地区：[1]兰州交通大学化学与生物工程学院,甘肃兰州730070

出　　处：《化工中间体》2010年第9期35-37,共3页

基　　金：兰州交通大学青蓝人才工程基金资助项目(QL-06-01A)

摘　　要：本论文对Wittig反应合成α,β-不饱和酯后处理做了改进。利用副产物三苯基氧膦易结晶的特点,先用重结晶的方法除去大部分副产物三苯基氧膦后,再用柱层析色谱法纯化得到产物。该方法不但减少了硅胶和洗脱剂的用量,而且使分离效果更好,具有一定的经济和环保意义。The present paper has made an improvement to the post-processing of Wittig reaction Synthesis ofα,β-unsaturated ester.The products were purified by column chromatography after the majority of the by-product triphenylphosphine oxide was removed by recrystallization due to its characteristic of easy-crystallization.This method diminished the use of silica gel and the eluent and made the separation more efficient.So it proved to be an economical and environmentally benign method.

关 键 词：WITTIG反应 Α Β-不饱和酯 三苯基氧膦 

分 类 号：TQ225.241[化学工程—有机化工]