缺血性中风急性期痰热证的证候演变特点及其与神经功能缺损程度的关系  

Dynamic Evolutive Rule of the Phlegm-fire Syndrome in Acute Ischemic Stroke and the Ralationship Between Neurological Parafunction and Different forms of Evolution of the Syndrome

作　　者：辛喜艳[1] 张华[1] 高颖[1] 

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《辽宁中医杂志》2010年第9期1644-1646,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：北京市科委资助项目(H020920010220);国家重点基础研究发展计划(973计划)资助项目(2003CB517102)

摘　　要：目的:探讨缺血性中风病急性期痰热证的证候演变特点及其与神经功能缺损程度的关系。方法:从数据库中提取67例5个时点(住院第1、2、3、7、14天)均进行了风、火、痰、瘀、气虚、阴虚阳亢6个证候要素评分和《美国国立卫生研究院神经功能缺损评分》(NIHSS)评分的痰热证患者的临床信息。采用频数统计、方差分析等方法研究缺血性中风急性期痰热证的演变特点及不同演变形式与神经功能缺损程度的关系。结果:在缺血性中风急性期痰热证的演变过程中,每个时点均以70%左右的概率保持原证候不变;中风病急性期痰热证始终保持不变组与某个时点发生证候变化组相比,其NIHSS在入院第7、14天有统计学差异。结论:缺血性中风急性期痰热证维持时间较长,不易发生证候变化;痰热证的消失与神经功能缺损程度的改善有关,提示中风病急性期针对痰热证积极治疗对促进神经功能恢复有意义。Objective：To investigate the dynamic evolutive rule of the phlegm -fire syndrome in Acute ischemic stroke and explore the ralationship between neurological parafunction and different forms of evolution of the phlegm -fire syndrome. Methods：The Clinical information of 67 phlegm-fire syndrome patients with acute ischemia stroke were extracted including their scores of six syndrome factors（ wind,fire,phlegm,stasis,qi -deficiency and hyperactivity of yang due to yin -deficiency） and the National Institutes of Health Stroke Scale（ NIHSS） on No. 1 ,2,3,7,14 day after their hospitalization. The evolution characteristic of the phlegm -fire syndrome and the ralationship between neurological parafunction and different forms of evolution of the syndrome were studied by using the methods of Descriptive Statistics and one -way ANOVA. Results：During the evolution of the phlegm-fire syndrome,conversion probability was about 70% of still further into the original syndrome. The NIHSS score was different because of different forms of evolution of the syndrome. And the differences in NIHSS scores had Statistical significance in 7th and 14th days. The NIHSS score change was hidden in unchanged group,and it was obvious in the changed group. Conclusion：Phlegm-fire syndrome is a Persistent factor In acute ischemia stroke and the disappear of phlegm-fire syndrome is relationed with the improvement of level of neurological parafunction,so it is Meaningful to positively eradicating the phlegm-fire syndrome in In acute ischemia stroke.

关 键 词：中风病 痰热证 证候演变 神经功能缺损 

分 类 号：R255.2[医药卫生—中医内科学]