水相中马尿酸分子印迹聚合物的制备及其性能研究  

Preparation of molecularly imprinted polymer of hippuric acid and its characteristics in the aqueous phase

作　　者：张建平[1] 苏立强[2] 王滨生[1] 

机构地区：[1]黑龙江省质量监督检测研究院,黑龙江哈尔滨150001 [2]齐齐哈尔大学化学与化学工程学院,黑龙江齐齐哈尔161006

出　　处：《化学工程师》2010年第9期10-12,共3页Chemical Engineer

基　　金：黑龙江省自然科学项目(B200911)

摘　　要：采用分子印迹技术,以马尿酸为模板分子,在水相中制备其印迹聚合物。用于液相色谱固定相,结果表明,该聚合物固定相表现出良好的分离选择性,能够使马尿酸与和其结构相似的苯甲酸及咖啡酸快速基线分离。并通过平衡吸附法分析了印迹聚合物的识别特性,结果表明分子印迹聚合物对马尿酸有特异性吸附。Molecular imprinted technology were used to prepare molecularly imprinted polymer in the aqueous phase useing hippuric acid as the imprinted molecule.And then the hppuric acid MIP is used liquid chromatogra-phy stationary phase,and the results of experiments showed that the stationary phase has a good selective and speration with structural analogues,and which can carry out baseline separation with benzoic acid and caffeic acid.The hppuric acid MIP show a well Specifically adsorption effect to the template Molecule by the analysis of equilibrium adsorption method.

关 键 词：分子印迹技术 马尿酸 高效液相色谱 

分 类 号：O657.7[理学—分析化学]