高压氧和小脑顶核电刺激治疗中重度颅脑损伤临床疗效比较  

Comparative study of the therapeutic effects between hyperbaric oxygen and fastigial nucleus stimulation on moderate or severe craniocerebral injury

作　　者：刘艳萍[1] 吴冰洁[1] 田松波[1] 王长春[1] 张会萍[1] 薛新萍[1] 

机构地区：[1]河北医科大学第二医院高压氧治疗科,石家庄市050000

出　　处：《河北医药》2010年第18期2482-2483,共2页Hebei Medical Journal

摘　　要：目的比较高压氧和小脑顶核电刺激治疗中度颅脑损伤患者的临床疗效。方法中重度颅脑损伤(GCS评分4～10分)患者140例,随机分为高压氧治疗组71例和电刺激治疗组69例,治疗前后采用功能障碍评分(DRS)和日常生活活动能力评分(Barthel指数),根据临床四级疗效标准进行疗效评定。结果高压氧治疗组和电刺激治疗组均能降低颅脑损伤患者DRS,提高BI,与治疗前比较差异有统计学意义(P<0.01)。高压氧治疗组总有效率(92.9%)高于电刺激治疗组(81.2%),差异有统计学意义(P<0.05)。结论中重度颅脑损伤患者高压氧治疗的临床疗效优于小脑顶核电刺激治疗。Objective To compare the therapeutic effect between the hyperbaric oxygen and fastigial nucleus stimulation（ FNS） on the moderate or severe craniocerebral injury. Methods 140 patients with moderate or severe craniocerebral injury （ GCS score 4 ～ 10） were randomly divided into hyperbaric oxygen treatment group （ n =71） and fastigial nucleus stimulation treatment group（ n =69） . The therapeutic effects before and after teat- ment were evaluated according to dementia rating scale（ DRS） and activities of daily living activity rating scale （ Barthel index） . Results Both hyperbaric oxygen treatment group and fastigial nucleus stimulation treatment group could decrease craniocerebral injury DRS,and improve the activities of daily living activity rating scale. There were significant differences before and after treatment （ P 0. 01） . The total effective rate in hyperbaric oxygen treatment group （ 92. 9% ） was significantly higher than that （ 81. 2% ） of fastigial nucleus stimulation treatment group （ P 0. 05） . Conclusion The therapeutic effect of hyperbaric oxygen is superior to that of fastigial nucleus stimulation on moderate or severe craniocerebral injury.

关 键 词：高压氧 小脑顶核电刺激 颅脑损伤 疗效 

分 类 号：R651.15[医药卫生—外科学]