脑卒中继发癫痫的临床研究  

Clinical study on post-stroke secondary epilepsy

作　　者：曾杨滨[1] 陆兵勋[2] 

机构地区：[1]广州医学院第三附属医院神经内科,广州510150 [2]南方医科大学南方医院神经内科,广州510515

出　　处：《广东医学》2010年第18期2370-2372,共3页Guangdong Medical Journal

基　　金：广东省医学科研基金资助项目(编号:A2008290)

摘　　要：目的探讨脑卒中与继发癫痫的关系。方法回顾分析1 475例经颅脑CT/MRI证实且无癫痫病史的脑卒中患者临床资料,调查脑卒中继发癫痫的发生率、发生时间、发作类型、抗癫痫药物治疗等。分析继发癫痫及与不同脑卒中类型、卒中病因、卒中评分、卒中部位、卒中并发症等因素的相关性。结果脑卒中继发癫痫发生率为8.68%(128/1 475)。继发癫痫与病变部位有关,累及皮层者易患,并与电解质酸碱失衡有相关性。抗癫痫治疗效果良好。结论脑卒中是继发性癫痫发作的原因之一,加强对脑卒中患者病情观察和治疗,积极防治并发症,有助于减少继发癫痫发生,减轻继发癫痫病情,以利于改善脑卒中患者预后。Objective To investigate the correlation between stroke and epilepsy.Methods A retrospective analysis of 1 475 cases of stroke proved with CT/MRI without epilepsy history was performed by reviewing clinical data including the prevalence of post-stroke secondary epilepsy,occurrence frequency,type of epilepsy and antiepilepsy therapy,etc.Correlation analysis between epilepsy seizure occurrence and stroke related factors： type of stroke,cause,stroke score,lesion location and complications was performed.Results The prevalence of post-stroke secondary epilepsy was 8.68%（128/1 475）.The epilepsy seizure was significantly correlated with cortex lesions and electrolyte acid-base disorder.The outcome of antiepileptic treatments was satisefactory.Conclusion Stroke is one of the causes of secondary epilepsy seizures.Close monitoring and antiepileptic treatment will be helpful in prevention of seizures and in improving the prognosis stroke.

关 键 词：脑卒中 癫痫 继发 

分 类 号：R473.74[医药卫生—护理学]