前列地尔联合疏血通治疗糖尿病周围神经病变的疗效观察  

The therapeutic efficacy of Lipo PGE combined with Shuxuetong injection in treatment of diabetic peripheral neuropathy

作　　者：张小东[1] 陈岚[1] 

机构地区：[1]江苏省靖江市人民医院内分泌科,214500

出　　处：《中华老年医学杂志》2010年第8期656-657,共2页Chinese Journal of Geriatrics

摘　　要：目的 观察前列地尔（凯时）联合疏血通静脉滴注对糖尿病周围神经病变（DPN）的疗效.方法 将68名DPN患者分为两组,治疗组凯时＋疏血通静脉滴注;对照组为疏血通静脉滴注,疗程均为14 d.结果 治疗组患者四肢疼痛、麻木、感觉异常等症状较对照组明显减轻（P＜0.01）,同时正中神经、腓肠神经的传导速度较治疗前明显加快（P＜0.05）,对照组治疗前后变化差异无统计学意义（P＜0.05）.结论 凯时联合疏血通治疗DPN是安全有效的方法.Objective To observe the efficacy of Lipo PGE combined with Shuxuetong injection in treatment of diabetic peripheral neuropathy （DPN）. Methods The 68 DPN patients were randomly divided into treatment group with Lipo PGE plus Shuxuetong injection and comparison group with Shuxuetong alone. The treatment period was 14 days. Results The pain, numbness,paresthesia and other symptoms in the limbs of patients were significantly reduced in treatment group than in comparison group （P〈0. 01）. At the same time, the conduction velocity of median nerve and sural nerve was significantly increased in treatment group after treatment （P〈0.05）, there were no significant differences in comparison group before and after the treatment. Conclusions The treatment of DPN with Lipo PGE combined with Shuxuetong injection is safe and effective.

关 键 词：糖尿病神经病变 前列地尔 药物疗法 联合 

分 类 号：R587.2[医药卫生—内分泌]