4-氨基苯基马来酰亚胺的合成研究  

Study on the Synthesis of 4-Aminophenyl Maleimide

作　　者：陶果[1] 

机构地区：[1]四川职业技术学院,四川遂宁629000

出　　处：《广州化工》2010年第9期59-61,127,共4页GuangZhou Chemical Industry

基　　金：四川省科技厅科技支撑基金项目(2010GZ0131)

摘　　要：以顺丁烯二酸酐和对硝基苯胺为原料,经多步反应合成了4-硝基苯基马来酰亚胺(Ⅰ)与4-氨基苯基马来酰亚胺(Ⅱ)两种新型NPMI产品,并采用傅立叶红外光谱和核磁共振氢谱对其结构进行了确认。同时研究了反应物摩尔比、催化剂用量、胺化反应温度等因素对合成4-硝基苯基马来酰亚胺的影响,以及考察了氯化亚锡用量、催化还原温度、盐酸用量等对合成4-氨基苯基马来酰亚胺的影响。产物(Ⅰ)收率达85%以上,产物(Ⅱ)收率在50%左右。4-Nitrophenyl maleimide（Ⅰ） and 4-aminophenyl maleimide（Ⅱ） as two news NPMI products were synthesized with a few-step methods from maleic anhydride and p-nitroaniline.The two news NPMI products construction were characterized by Fourier transform infrared spectroscopy FTIR and 1HNMR.And the affecting factors of the synthesis of 4-nitrophenyl maleimide were studied,such as mole number ratio of reactants,catalyst amount and aminate temperature.The affecting factors of the synthesis of 4-aminophenyl maleimide were studied too,as amount of stannous chloride,reduction temperature and amount of hydrochloric acid.The yield of product（Ⅰ） was up to 85% and the yield of product（Ⅱ） was about 50%.

关 键 词：4-氨基苯基马来酰亚胺 4-硝基苯基马来酰亚胺 顺丁烯二酸酐 对硝基苯胺 

分 类 号：TQ245.27[化学工程—有机化工]