宫颈粘液过氧化物酶在月经周期中的变化规律  

REGULATION OF CERVICAL MUCUS PEROXIDASE DURING MENSTRUAL CYCLES

作　　者：王红[1] 曹缵孙[1] 翁其亮[2] 王秉正[1] 王民[3] 毛文军[1] 

机构地区：[1]西安医科大学第一附属医院妇产科 [2]西安医科大学化学教研室 [3]西安医科大学组胚教研室

出　　处：《生殖与避孕》1990年第4期9-14,共6页Reproduction and Contraception

基　　金：国家自然科学基金

摘　　要：本文对29例月经周期正常妇女的宫颈粘液过氧化物酶进行了30个周期的研究。在月经周期不同时间测定宫颈粘液过氧化物酶(CMPx)活性及血清促黄体生成素(LH)、雌二醇(E_2)和孕酮(P)。结果表明:在排卵前三天酶活性明显下降,至排卵后一天开始上升。卵泡期,酶活性与E_2呈负相关(r=-0.67);黄体期,酶活性与P呈正相关(r=0.79)。本研究提示:1.CMPx在排卵周期具有特定的变化规律,其变化受体内激素水平影响,可作为预告排卵的指标。2.如简化测定方法,可为自然避孕提供新途径。Twenty-nine infertile women with normal menstrual cycles were observed for overall 30 cycles. Peroxidase activity in cervical mucus (CMPx), serum Iuteinizing hormone (LH), estradiol (E_2) and progesterone (P) were measured during the menstrual cycles. Data thus obtained demonstrated that CMPx activity fell down and remained at a lower level for three days before ovulation and rose up again one day after ovulation. In the follicular phase, there was a negative correlation between CMPx and E_2 (r= -0.67): and in the luteal phase, there was a positive correlation between CMPx and P (r=0.79). The results suggest: !. CMPx has a regular special change during ovulatory cycles and may be affected by hor- mones. Thus it can be used as a predictor of ovulation. 2. If the procedure of CMPx measurement can be simplified, it may be used as a more effective method for natural family planning to detect the fertile period.

关 键 词：月经周期 宫颈粘液 过氧化物酶 

分 类 号：R711.51[医药卫生—妇产科学]