舒芬太尼与曲马多用于小儿PCIA的临床效果观察  

Clinical investigation of the postoperative controlled intravenous analgesia with sufentanil and tramador in children.

作　　者：徐晓燕[1] 黄振华[1] 张成[1] 

机构地区：[1]成都市儿童医院,四川成都610017

出　　处：《中外医学研究》2010年第19期16-18,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的观察舒芬太尼和曲马多用于学龄期小儿全麻手术术后自控镇痛的效果。方法80例择期手术患儿，ASAⅠ～Ⅱ级，年龄≥6岁，随机分为两组。S组用舒芬太尼0．04μ／kg·h，T组用曲马多0．4mg／kg·h分别进行术后自控镇痛。观察并记录术后4h,8h、16h、24h和36h的心率、平均动脉压、呼吸频率、VAS评分、Ramsay评分和术后48h内镇痛泵按压次数、实进次数、按压次数／实进次数比值等指标，以及不良反应的发生情况。结果术后4h、8h、16hS组VAS评分低于T组（P〈0．05），术后48h内S组镇痛泵按压次数、实进次数均少于T组（P〈0．05）。结论舒芬太尼和曲马多用于小儿术后镇痛都安全有效，但舒芬太尼效果优于曲马多。Objective To compare the analgesia effect of sufentanil and Tramadol for PCIA in children. Methods Eighty ASA Ⅰ～Ⅱ patients （age≥6 years） were randomized to two groups. Sufentanil 0. 04 μg/kg·h was administered in Group S while tramadol 0.4 mg/kg·h in Group T. Outcome including HR, MAP, RR, VAS score and Ramsay score at 4,8,16,24,36 hours after operation, were observed. Otherwise, the frequency of actuality press, frequency of utility press and frequency of actuality of press/frequency of utility press as well as side effect were recorded. Results VAS score of Group S lower than Group T（P 〈 0. 05）. Moreover, both frequency of actuality press and frequency of utility press of Group S were less than Group T（P 〈 0. 05）. Conclusion Both sufentanil and Tramadol are safe and effective for PCIA in children, but the analgesia effect of sufentanil is better than Tramadol.

关 键 词：舒芬太尼 曲马多 小儿术后镇痛 

分 类 号：R614.24[医药卫生—麻醉学]