新诊断2型糖尿病患者周围神经病变临床分析  

Clinical Analysis of Peripheral Neuropathy in Type 2 Diabetes Newly Diagnosed

作　　者：王增军[1] 田作荣[1] 马绍刚[1] 

机构地区：[1]徐州医学院附属淮安医院神经内科,江苏省淮安市223002

出　　处：《医学理论与实践》2010年第10期1188-1189,1204,共3页The Journal of Medical Theory and Practice

摘　　要：目的:探讨新诊断2型糖尿病(T2DM)患者周围神经病变相关临床危险因素。方法:随机选择172例新诊断T2DM,经过神经传导速度测定分为神经病变(DPN)组和非DPN组,比较两组临床参数血糖、血压、血脂等,数据经统计学处理。结果:共检出DPN患者49例,DPN患病率为28.4%,DPN组的年龄、收缩压和HbA1c均显著高于非DPN组,差异具有统计学意义(P<0.05),其余各项指标两组间差异均无统计学意义,经Logistic分析HbA1c是DPN的危险因素。结论:新诊断T2DM神经病变发生率较高,HbA1c是DPN的危险因素。Objective：To investigate the clinical risk factors in type 2 diabetic newly diagnosed with peripheral neuropathy.Methods：172 diabetics newly diagnosed were selected randomly.They were divided into peripheral neuropathy group（DPN）and no peripheral neuropathy group（non-DPN）according to the nerve conduction velocity（NCV）.Clinical characteristics,including blood pressure,fasting and postprandial blood glucose,HbA1c,lipid profiles,uric acid,insulin and urinary albumin（uAlb） were determined.Data was evaluated using analysis of SPSS11.0.Results：49 diabetics were screened.The DPN group showed older age（58.6±8.3 vs 50.9±5.2,yrs）,higher systolic blood pressure（139.3±20.0 vs 128.8±10.2,mmHg）and higher HbA1c（9.8±2.5 vs 7.9±2.3,%）,P0.05.Logistic analysis screened that HbA1c was the independent risk factors for DPN（P0.05）.Conclusion：DPN had higher incidence in T2DM newly diagnosed.Hyperglycemia was important risk factors.

关 键 词：2型糖尿病 周围神经病变 危险因素 

分 类 号：R587.1[医药卫生—内分泌]