低剂量复合螺旋藻多糖抗衰老作用研究  

Study on Anti-aging Function of Low-dosage Compound Spirulina Polysaccharides

作　　者：唐纯青[1] 于蕾妍[2] 张丽[2] 高玲[2] 王清吉[2] 

机构地区：[1]山东省济南市第五人民医院内三科,山东济南250022 [2]青岛农业大学生科院,山东青岛266109

出　　处：《安徽农业科学》2010年第20期11036-11038,共3页Journal of Anhui Agricultural Sciences

摘　　要：每天给小鼠灌服50mg/kg复合药物,同时每天给其颈背皮下注射D-半乳糖125mg/kg,连续造模42d后观察低剂量复合螺旋藻多糖、银杏叶提取物对D-半乳糖致衰老小鼠的作用,测定免疫器官的重量、血清SOD活性及心肌、脑丙二醛(MDA)含量等相关衰老指标。结果表明,低剂量复合螺旋藻多糖可显著对抗连续42d给D-半乳糖125mg/(kg.d)所致小鼠衰老。The mice were drenched with 50 mg/kg compound medicine and simultaneously injected with 125 mg/kg D-galactose by hypodermic injection in nape everyday.After continuously modeling for 42 d,the effects of low-dosage compound spirulina polysaccharides and gingko leaf extracts on D-galactose-caused aged mice were observed and the aging-related indexes of weight of immune organ,SOD activity in serum,MDA contents in cardiac muscle and brain were determined.The results indicated that low-dosage compound spirulina polysaccharides had significant anti-aging effect on aged mice,which were modeled by continuously giving 125 mg/（kg.d）D-galactose for 42 d.

关 键 词：螺旋藻多糖 银杏叶提取物 D-半乳糖 衰老 

分 类 号：R965[医药卫生—药理学]