拔伸松动法治疗兔膝骨性关节炎的实验研究  

An Experimental Study on the Treatment of Rabbits with Knee Osteoarthritis by Traction and Looseness Therapy

作　　者：王春林[1] 向勇[2] 田启东[2] 夏惠明[1] 赵志勇[1] 胡鸾[1] 钱忠义[3] 邵长丽[2] 杨茜[1] 

机构地区：[1]云南中医学院第一附属医院推拿科,云南昆明650021 [2]云南中医学院,云南昆明650200 [3]昆明医学院病理教研室,云南昆明650031

出　　处：《云南中医中药杂志》2010年第9期54-55,共2页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：云南省教育厅科研基金资助项目(编号:5Z0477C)

摘　　要：目的:研究拔伸松动法对膝关节骨性关节炎治疗的作用机制。方法:采用成年日本大白兔,按Videman T的造模方法制作兔膝骨性关节炎模型,随机分为实验组和对照组2组,实验组实施拔伸松动法,对照组正常饲料喂养。观察2组实验前后关节活动度、X线表现及光镜下关节软骨的病理变化。结果:实验组能明显改善关节活动度,与对照组比较,有显著性差异(P<0.01);X线表现:实验组较实验前关节间隙略显增宽,而骨质未见明显改变;光镜检查:实验组:软骨层软骨表面光滑,软骨细胞数量增多,软骨细胞增殖明显,细胞排列整齐,层次清楚,潮线完整,基质染色均匀。对照组:软骨层软骨表面欠光滑,软骨细胞数量减少,排列不整齐,软骨细胞增殖不明显,软骨基质增多,层次不清楚,潮线紊乱,基质染色欠均匀。结论:拔伸松动法能明显改善膝关节活动度,有利于DOA退变的软骨组织的修复。Objective:To study the function and mechanism of the treatment of knee osteoarthritis by traction and looseness therapy.Methods:Japanese adult rabbits were used to make rabbit models with knee osteoarthritis according to Videman T and were randomly divided into a test group and a control group.The test group was treated with the traction and looseness therapy while the control group was given normal feed.The joint activities,X ray and the pathologic changes of articular cartilage under filter lens were observed before and after the experiments.Results:The joint activities in the test group obviously improved and showed significance difference comparing with that of the control group(P<0.05).X ray showed the joint space in the test rabbits was slightly wider than that before the test while the bone was not altered significantly.The filter lens examination in the test group showed the cartilage surface was smooth,the number of the cartilage cells increased and the cartilage cells proliferated with neatly arranged cells,clear layers and complete tide line and even ground dyeing while the filter lens examination in the control group showed the cartilage surface was unsmooth,the number of the cartilage cells decreased with irregularly arranged cells,unobvious proliferation,unclear layers,disordered tide line and uneven ground dyeing.Conclusion:The traction and looseness therapy can greatly improve the knee joint activities and is helpful to the repair of the cartilage.

关 键 词：拔伸松动手法 膝骨性关节炎 实验研究 

分 类 号：R285.5[医药卫生—中药学]