2型糖尿病早期肾损害的彩色多普勒超声诊断研究  

Diagnostic Valure of Color Doppler Ultrasound for Early Renal Damage of Type 2 Diabetic

作　　者：赵胜利[1] 李秀芬[1] 耿喆[1] 

机构地区：[1]山东省聊城市第二人民医院超声科,252600

出　　处：《中国全科医学》2010年第26期2910-2912,共3页Chinese General Practice

摘　　要：目的评价彩色多普勒超声检查在2型糖尿病(T2DM)早期肾损害诊断中的应用价值。方法选取102例T2DM患者,按尿清蛋白排泄率(UAER)将其分为3组:A组(UAER<20μg/min)、B组(UAER在20～200μg/min)和C组(UAER>200μg/min)。同时选择32例健康者作为对照组(D组)。应用彩色多普勒超声仪检查4组受检者的肾脏大小、血流灌注情况及肾脏各级动脉血流动力学参数。结果与D组比较,A、B、C组患者的肾脏体积均显著增加,差异有统计学意义(P<0.01)。与A、D组比较,B组、C组各级动脉的搏动指数(PI)、阻力指数(RI)均显著增高,而收缩期最大血流速度(Vmax)、舒张期最低血流速度(Vmin)均显著降低,差异有统计学意义(P<0.05);A组的各级血流频谱参数虽有变化,但与D组比较差异无统计学意义(P>0.05)。随肾脏损害程度的加重,肾彩色血流显像逐渐减少,D组及A组的血流显像均为Ⅰ级或Ⅱ级,B组主要为Ⅲ级,C组主要为Ⅳ级。结论彩色多普勒超声能提示T2DM患者肾脏大小、血流灌注情况及肾血流动力学情况,对早期糖尿病肾病的诊断是有价值的。Objective To assesses the value of color Doppler ultrasonography in reflecting early diabetic nephropathy（DN）.Methods 102 cases with type 2 diabetes were classified into three groups according to the urinary albumin excretion（UAER）：group A（UAER20 μg/min）,group B（UAER 20～200 μg/min）,and group C（UAER200 μg/min）.32 normal persons were selected as controls（group D）.In each group,renal size,biood flow distribution conditions,and blood flow parameters of objects in four groups were measured.Results Compared with group D,the renal size in diabetic patients were different extent larger（P0.01）;Comparied with group A and D,the RI and PI of renal arteries in patients in group B and C were higher,the Vmax and Vmin were lower（P0.05）.There were no significant differences in the flow parameter between patients in group A and group D（P0.05）.The more severe the condition was,the more obvious the decrease of blood flow was,group D and group A showed as typeⅠor type Ⅱ,group B showed as type Ⅲ,group C showed as type Ⅳ.Conclusion Color Doppler ultrasound is a useful method for assessment of renal size,biood flow distribution and blood flow parametersand and for early diagnosis and evaluation of diabetic nephropathy.

关 键 词：超声检查 多普勒 彩色 糖尿病 2型 糖尿病肾病 肾动脉 血流动力学 

分 类 号：R587.24[医药卫生—内分泌]