2,2-二甲基-1,5-二氧杂菲-6-酮的微波合成研究  

Study on the microwave synthesis of seselin

作　　者：丁恒良[1] 孙宏顺[1] 徐宏[1] 

机构地区：[1]南京化工职业技术学院,江苏南京210048

出　　处：《化学工业与工程技术》2010年第4期12-15,共4页Journal of Chemical Industry & Engineering

摘　　要：以7-羟基香豆素和3-氯-3-甲基-1-丁炔为原料,分别采用不同的微波合成条件,经两步合成2,2-二甲基-1,5-二氧杂菲-6-酮。实验结果表明,与传统合成方法相比,微波合成不仅大大减少了反应的时间,还降低了原料的消耗,是合成Seselin的较优方法。Used umbelliferone and 3-chloro-3-methyl-1-butyne as feed stock,the seselin is synthesized by method of microwave irradiation in two steps.In each step,a different microwave condition is given.The experiment results show that MW-synthesis can not only greatly reduce the reaction time,but also reduce the consume of the expensive material campared with traditional conditions,it＇s a better way to synthesize the Seselin.

关 键 词：微波合成 2 2-二甲基-1 5-二氧杂菲-6-酮 7-羟基香豆素 3-氯-3-甲基-1-丁炔 

分 类 号：TQ254.2[化学工程—有机化工]