中药对肝动脉栓塞化疗所致肝损害的疗效观察  

Clinical Study on Effect of Chinese Herbal Medicine on Liver Damage Caused by Hepatic Artery Chemoembolization

作　　者：刘城林 蔡悦成[1,2,3] 黄政叶 古云林 刘瑞萍[1,2,3] 

机构地区：[1]广东省肇庆市中医院 [2]广东省肇庆市第一人民医院 [3]广西省南宁市职工康复医院

出　　处：《中国中西医结合杂志》1999年第5期276-278,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的：探讨中药对肝动脉栓塞化疗所致肝损害的治疗效果。方法：总结采用Ｓｅｌｄｉｎｇｅｒ′ｓ技术行肝动脉栓塞化疗１１０例，随机分为Ａ、Ｂ两组。Ａ组６０例为中药治疗组，以中药清肝解毒散结汤随症加减治疗；Ｂ组５０例为西药常规治疗组。观察两组肝功能变化、肝硬变发生率及加重率。结果：按Ｃｈｉｌｄ′ｓ肝功能分级标准，结果肝功能下降的总体发生率Ａ组为４６６７％、Ｂ组为６８００％，Ａ组低于Ｂ组（Ｐ＜００５）。肝硬变发生率及加重率：Ａ组分别为３５００％（７／２０例）、５０００％（２０／４０例）；Ｂ组分别为６５００％（１３／２０例）、７６６７％（２３／３０例），两组比较均有显著性差异（Ｐ＜００５）。结论：中药清肝解毒散结汤对肝动脉栓塞化疗所致肝损害有减轻和预防作用。Objective: To observe the effect of Chinese herbal medicine on hepatic artery chemoembolization caused liver damage. Methods: One hundred and ten patients, who received hepatic artery chemoembolization, were divided into two groups, 60 patients in the treated group were treated with Qinggan Jiedu Sanjie Decoction and the other 50 Patients in the control group treated with routine western medicine. The changes of liver function, cirrhosis incidence and exacerbation rate of both groups were observed. Results: The total liver function deterioration rate of the treated group, according to Child′s grading standard, was 46.67%, while that of the control group was 68.00%, the former was much lower than the latter (P<0 05). The cirrhosis incidence and exacerbation rate in the treated group were 35.00% (7/20) and 50.00% (20/40) respectively, while in the control group, they were 65.00% (13/20) and 76.67% (23/30) respectively. The difference between the two groups was also significant (P<0 05). Conclusion: Qinggan Jiedu Sanjie Decoction has some effect on alleviating and preventing hepatic damage caused by hepatic artery chemoembolization.

关 键 词：肝肿瘤 栓塞化疗 肝功能 中药 治疗 

分 类 号：R273.57[医药卫生—中西医结合]