丙肝抗体阳性患者血清中HCV核心抗原的检测  

Detection of HCV core antigen in serum of HCV antibody positive patients

作　　者：阮光萍[1] 姚翔[1] 王桂华[1] 潘兴华[1] 

机构地区：[1]解放军昆明总医院临床实验科,云南昆明650032

出　　处：《医学信息（中旬刊）》2010年第10期2995-2996,共2页Medical Information Operations Sciences Fascicule

摘　　要：目的:应用ELISA方法检测丙肝抗体阳性血清标本中的HCV核心抗原,分析和评价HCV核心抗原检测的在献血员筛查中的意义。方法:对丙肝抗体弱阳性标本14例和强阳性标本9例和阴性标本18例,用ELISA方法检测标本中的HCV核心抗原。结果:14例弱阳性标本中有10例HCV核心抗原为阳性,9例强阳性标本中仅有1例HCV核心抗原为阳性,18例阴性标本中有1例HCV核心抗原为阳性。结论:HCV核心抗原检测必须结合HCV抗体检测,仅用HCV核心抗原检测会漏检HCV抗体强阳性的标本。Objective：ELISA methods were used to detect HCV core antigen in serum of HCV antibody positive sample.Analysis and value of the significance of detection of HCV core antigen in donors screening.Methods：HCV core antigen were detected by ELISA methods in 14 HCV antibody weakly positive,9 anti-HCV antibody strong positive and 18 negative serum.Results：10 HCV core antigen is positive in 14 HCV antibody weakly positive serum.Only 1 HCV core antigen is positive in 9 anti-HCV antibody strong positive sample.1 HCV core antigen is positive in 18 negative serum.Conclusion：It is necessary to combine the detections of HCV core antigen and HCV antibody.Only use of HCV core antigen detection will undetect anti-HCV antibody strong positive sample.

关 键 词：丙肝病毒抗体 丙肝病毒核心抗原 HCV 

分 类 号：R446.61[医药卫生—诊断学]