慢性肾脏病患者高血压发病机制新进展  

New Advances in the Pathogenesis of Hypertension in Patients with Chronic Kidney Disease

作　　者：黄珍珍[1] 任伟[1] 

机构地区：[1]安徽医科大学附属省立医院肾内科

出　　处：《国际老年医学杂志》2010年第5期214-219,共6页International Journal of Geriatrics

摘　　要：传统观点将慢性肾脏病的高血压发病机制分为容量依赖型和肾素依赖型两种,但这并未完全阐明肾脏疾病时高血压的发生机制。因为近年来,人们发现在减少血容量和抑制肾素—血管紧张素系统之后,仍不能有效控制血压,从而一些新的机制被提出。本文着重对这些尚未完全公认的发病机制作一综述。The traditional opinions are that pathogenesis of hypertension in patients with chronic kidney diseese （CKD） is due to an excess of intravascular volume （volume dependent） or excessive activation of the renin- angiotensin system （renin -dependent）. In recent years, this concept has been challenged by some new mechanisms, it is owing to the recognition that interventions aimed at reducing blood volume and inhibiting the renin - angiotensin system often do not normalize blood pressure （BP）. This review will focus on the new mechanisms.

关 键 词：肾脏病 慢性 高血压 发病机制 综述 

分 类 号：R692[医药卫生—泌尿科学]