胎儿不同程度侧脑室扩张的产前超声诊断及预后  

Antenatal Diagnosis and Prognosis of Fetal Lateral Ventriculomegaly in Different Degrees by Ultrasound

作　　者：黄凤华[1] 肖立平[1] 徐宜咏[1] 张元珍[1] 

机构地区：[1]武汉大学中南医院妇产科,湖北武汉430071

出　　处：《武汉大学学报（医学版）》2010年第5期654-657,共4页Medical Journal of Wuhan University

摘　　要：目的:研究胎儿不同程度侧脑室扩张的产前超声诊断及临床预后,为遗传咨询及临床处理提供依据。方法:采用彩色超声诊断仪对孕妇作产前超声检查,发现胎儿侧脑室扩张时,测量侧脑室宽度并进行分度,对每一例胎儿进行超声动态监测和随访,部分孕妇行羊膜腔穿刺检测胎儿染色体。结果:116例胎儿有侧脑室扩张,在妊娠中晚期引产51例,占44%。轻度侧脑室扩张组78例,引产17例,占21.79%,均合并其他畸形;重度侧脑室扩张组38例,引产34例,占89.47%,多合并其他畸形。轻度组未引产胎儿61例,31例胎儿的侧脑室扩张在出生前自然消失,占50.82%;6例胎儿侧脑室扩张加重,占9.83%;其余24例持续存在,占39.34%。重度组未引产胎儿4例,1例死产,3例在出生后6月内死亡。53例行胎儿染色体检测,发现染色体核型异常12例,占23.53%。结论:单纯的轻度侧脑室扩张,50%可在出生前自然消失,40%持续存在,极少数加重;轻度侧脑室扩张合并神经系统或其它器官畸形;重度侧脑室扩张胎儿预后差,多行引产术。Objective：To study the value of ultrasound in antenatal diagnostic and prognostic evaluation of fetal lateral ventriculomegaly.Methods：The pregnant women with fetal lateralventriculomegaly undertook ultrasonic examination and were followed up for six months after birth.The degrees of fetal lateral ventriculomegaly were measured and recorded.Fifty-three cases underwent amnio-centesis for chromosome karyotype analysis.Results：There were 116 cases with different degrees of lateral ventriculomegaly,of which,51 cases underwent artificial labor in gestation stage,including 17 cases in mild degree and 34 cases in severe degree.Of the other 65cases without artificial labor,61 cases were in mild group,including 31 cases（50.82%）whose venticulomegaly gradually disappeared,6 cases（9.83%）became more serious,and 24 cases（39.34%）kept existence.The other 4cases without artifcial labor were in severe grade,including one was dead-birth and three died in six months after birth.Twelve（23.53%） of the 53cases underwent chromosome karyotype analysis showed chromosome abnormality.Conclusion：About 50% of simplex mild lateral ventriculomegaly vanished before birth,40%kept existence,and only very few became more serious.The lateral ventriculomegaly would have a poor prognosis when complicates with other deformations or in severe degree,unless the pregnant women undertake artificial labor.

关 键 词：胎儿 侧脑室扩张 超声诊断 预后 

分 类 号：R714.7[医药卫生—妇产科学] R445.1[医药卫生—临床医学]