^(18)F-FDG PET/CT意外发现胃肠道局限性高代谢灶的临床意义  

Clinical value of ^(18)F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake

作　　者：张淼[1] 陈刚[1] 王超[1] 胡佳佳[1] 张敏[1] 徐昊平[1] 鲍昭芳[2] 李彪[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院核医学科,上海200025 [2]上海交通大学医学院附属瑞金医院特需门诊,上海200025

出　　处：《上海交通大学学报（医学版）》2010年第9期1043-1046,共4页Journal of Shanghai Jiao tong University:Medical Science

基　　金：上海市重点学科建设项目(S30203)~~

摘　　要：目的探讨18F-FDGPET/CT意外发现胃肠道局限性高代谢灶的临床意义。方法回顾性分析4188例进行18F-FDGPET/CT检查的病例,选择满足以下条件的病例作为研究对象:18F-FDGPET/CT检查中意外发现胃肠道局限性高代谢灶怀疑为恶性肿瘤,且在18F-FDGPET/CT检查前无相应部位的临床症状或影像学异常。共有45例病例入选,将PET/CT检查结果与病理结果进行对照。结果 4188例被检者中意外发现胃肠道高代谢灶45例(1.1%),失访5例,经病理证实异常者40例。其中恶性病变23例(57.5%),良性病变(癌前病变)2例(5%),炎性病变15例(37.5%)。胃肠道肿瘤组的SUVmax值为(9.8±4.5),高于炎症病变组的SUVmax值(6.5±2.5),差异有统计学意义(P<0.05)。结论 18F-FDGPET/CT意外发现的胃肠道局限性高代谢灶恶性肿瘤的可能性较大,需要给予足够的重视,对于无症状胃肠道肿瘤的早期发现和及时诊治具有重要意义。Objective To explore the clinical value of 18F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake.Methods The clinical data of 4 188 patients examined by 18F-FDG PET/CT were retrospectively analysed.Patients with unexpected gastrointestinal lesions with high uptake suspected of malignant tumors examined by 18F-FDG PET/CT,and without corresponding clinical symptoms and imaging abnormalities were selected.Forty-five out of 4 188 patients were enrolled,and the results of PET/CT examinations were compared with pathological findings.ResultsUnexpected gastrointestinal lesions with high uptake were detected in 45 out of 4 188 patients （1.1%）.Among the 45 patients,40 were confirmed by pathological examinations,and the other 5 were lost to follow up.Among the 40 patients,there were 23 cases （57.5%） of malignant lesions,2 cases （5%） of benign lesions （precancerous lesions） and 15 cases （37.5%） of inflammatory lesions.SUVmax of gastrointestinal tumors group （9.8±4.5） was significantly higher than that of inflammatory lesions group （6.5±2.5）（P0.05）.Conclusion The possibility of unexpected gastrointestinal lesions with high uptake detected by 18F-FDG PET/CT to be malignant ones is higher,and attention should be paid to the early detection and timely treatment of gastrointestinal tumors without symptoms.

关 键 词：正电子发射型体层摄影 胃肠道 肿瘤 

分 类 号：R817.4[医药卫生—影像医学与核医学] R735[医药卫生—放射医学]