硫酸钙人工骨材料应用于跟骨骨折12例  

Application of calcium sulfate artificial bone in 12 cases of calcaneal fractures

作　　者：王华[1,2] 张晓明[1,2] 林博文[1,2] 谢伟平 黎伟凡[1,2] 

机构地区：[1]暨南大学附属第二医院 [2]深圳市人民医院骨关节科,广东省深圳市518000

出　　处：《中国组织工程研究与临床康复》2010年第34期6457-6460,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：背景:目前治疗跟骨骨折的观点是手术复位后植骨修复骨缺损,但在骨缺损的填充物选择方面仍有不同的意见。目的:观察硫酸钙人工骨结合内固定置入物治疗跟骨骨折骨缺损的临床疗效。方法:自2007-10/2008-12采用硫酸钙人工骨植骨及接骨板置入内固定治疗SandersⅡ、Ⅲ型跟骨骨折12例。所有患者均采用跟骨外侧"L"形手术切口,将骨折复位后选取粉状或颗粒状硫酸钙人工骨植入,植骨后于跟骨外侧放置预弯好的树形接骨板置入内固定。术后每月门诊复查平片,8周起按照X射线片显示的骨折愈合情况指导患者部分负重锻炼,骨折愈合后患肢完全负重行走。手术前后采用Maryland评分评价患足功能。结果与结论:所有患者经7～18个月(平均11.2个月)随访,骨折平均愈合时间12周,根据Maryland足部评分系统,总优良率92%,所有患者无排斥反应、过敏反应及毒性反应。提示硫酸钙人工骨植骨结合切开复位内固定可有效治疗跟骨骨折;硫酸钙人工骨是一种良好的骨移植替代物。BACKGROUND：The current treatment of calcaneal fracture is bone graft repair of bone defects after reduction surgery,but the selection of the filling of bone defects is controversial.OBJECTIVE：To evaluate the clinical curative effect of calcium sulfate artificial bone and internal fixation for calcaneus fracture.METHODS：Twelve patients with Sanders type Ⅱ and Sanders type Ⅲ fractures of calcaneus underwent implantation of calcium sulfate artificial bone and internal fixation of bone plate in Shenzhen People＇s Hospital from October 2007 to December 2008.All patients were treated with lateral calcaneal L-shape incision,powdered or granular calcium sulfate bone graft was implanted after fracture reduction,then lateral calcaneus was placed the prebending tree-shape bone plate as internal fixation.The patients were monthly rechecked plain film in out-patient clinic,and were instructed to do some weight-bearing exercises after 8 weeks,in accordance with the fracture healing displayed in X-ray films,followed by a full weight-bearing walk after limb fracture healing.Functional results were assessed by Maryland Foot Score.RESULTS AND CONCLUSION：All patients were followed up 7-18 months（average 11.2 months） after operation.The average time of fracture healing was 12 weeks.According to the evaluation of Maryland Foot Score,the excellent and good results were noted 92%.No such complications as rejection,irritability and toxicity were discovered.Implantation of calcium sulfate artificial bone in combination with open reduction and internal fixation is an effective and secure method for fracture of calcaneus.calcium sulfate artificial bone is a good bone graft.

关 键 词：跟骨骨折 骨移植 硫酸钙 骨缺损 骨科生物材料 

分 类 号：R318[医药卫生—生物医学工程]