99↑Tc^m标记化合物显像检测冠心病的优化方案探讨  

The optimal program of 99Tcm labeled radionuclide imaging in diagnosing coronary disease

作　　者：栾兆生[1] 周雯[1] 唐为国[1] 杨曙光[1] 张杰[1] 刘文清[1] 王永清[1] 李乃义[1] 

机构地区：[1]中国人民解放军第88医院核医学科,山东泰安271000

出　　处：《国际放射医学核医学杂志》2010年第1期42-46,共5页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：目的 探讨99↑Tc^m标记化合物显像检测冠心病的优化方案.方法 选择临床可疑或确诊的冠心病患者4236例,进行99↑Tc^m标记化合物显像8873例次,分析显像结果,提出99↑Tc^m标记化合物显像检测冠心病的优化方案,并与临床资料对照验证.结果 在可疑冠心病诊断、心肌缺血检测、心肌梗死诊断中,该方案准确率高达94.1%.对临床特需的诊断要求如存活心肌检测、 ＂罪犯＂血管检测、缺血性心肌病诊断、疗效监测等也有较高的准确率.结论 99↑Tc^m标记化合物显像优化方案可以完成临床对冠心病的大部分诊断要求,克服了核素显像自身的部分缺陷,具有高效、简便、节约的优势,临床指导价值显著.Objective To investigate the optimal program of 99↑Tc^m labeled radionuclide imaging in diagnosing coronary disease. Methods Four-thousand-two-hundred and thirty-six patients who were suspected or diagnosed with coronary disease were chosen. Eight-thousand-eight-hundred and seventy-three times 99↑Tc^m labeled radionuclide imaging were taken and analyzed. The optimal program of 99↑Tc^m labeled radionuclide imaging were drawn, compared and verified with their clinical information. Results The optimal program had high accuracy in diagnosing the patients of coronary disease, myocardial ischemia, myocardial infarction. It also was exact in special clinical needs of detecting myocardial viability, culprit vessel, ischemic cardiomyopathy and therapy effect. Conclusions The optimal program could satisfy many requirements of diagnosing coronary disease and overcome some defects of radionuclide imaging. So it was one highperforming, convenient and economical program and had significant clinical value.

关 键 词：锝 放射性核素显像 冠状动脉疾病 

分 类 号：R541[医药卫生—心血管疾病]