人GLP-1类似物利拉鲁肽的最新研究进展  

The latest research progress of human GLP-1 analogues liraglutide

作　　者：杨文英[1] 

机构地区：[1]卫生部中日友好医院内分泌科,北京100029

出　　处：《中华内分泌代谢杂志》2010年第9期840-843,共4页Chinese Journal of Endocrinology and Metabolism

摘　　要：研究证实，新型胰升糖素样肽-1（GLP—1）类似物可以解决糖尿病治疗中存在的多种问题，因而受到各国学者的广泛关注。本文概括了GLP-1的生理作用和长效人GLP-1类似物利拉鲁肽的延长作用机制，同时重点介绍了利拉鲁肽的最新基础与临床研究进展。The novel drug class of Glucagon-like peptide-1 （ GLP-1 ） analogue is extremely promising, since they can address many of the unmet needs of diabetes treatment. This article summarized physiological action of GLP-1 and delayed mechanisms of long-acting human GLP-1 analogue liraglutide. Simultaneously, the latest basic and clinical research results of lirag]utide were reported especially.

关 键 词：胰升糖素样肽-1 利拉鲁肽 糖尿病 2型 

分 类 号：R587.1[医药卫生—内分泌]