青年腹型肥胖患者血液流变学和微量白蛋白尿的相关性研究  

Study on Hemorheology and Microalbuminuria in Young Abdominal Obesity

作　　者：刘志新[1] 林振[1] 蓝宇[1] 宋志彬[1] 伍业星 韦海潮 廖国柱 

机构地区：[1]广东省中山市小榄人民医院,528415

出　　处：《天津医药》2010年第10期846-848,共3页Tianjin Medical Journal

基　　金：广东省医学科研基金资助项目(项目编号:A2008825)

摘　　要：目的:探讨青年腹型肥胖患者微量白蛋白尿(MAU)、血液流变学及生化指标的相关性。方法:筛选青年腹型肥胖患者(腹型肥胖组)146例、外周型肥胖患者(外周肥胖组)143例和同期健康志愿者(健康对照组)145例,检测和比较3组MAU、血液流变学及生化指标,并进行相关性分析。结果:腹型肥胖组的MAU及血液流变学指标高于外周肥胖组、健康对照组,腹型肥胖组所有生化指标高于健康对照组,腹型肥胖组肌酐、血糖高于外周肥胖组,差异均有统计学意义(P<0.05或P<0.01)。腹型肥胖组的MAU与全血黏度、血浆黏度、红细胞比容、全血还原黏度、红细胞聚集指数、红细胞刚性指数、三酰甘油、血尿酸、尿素氮、肌酐、血糖均呈正相关(P<0.05或P<0.01),与红细胞变形指数、红细胞电泳指数则呈负相关(P<0.05)。结论:青年腹型肥胖患者存在不同程度MAU、血液流变学及生化指标异常,且MAU与血液流变学及生化指标具有相关性。Objective：To investigate the relativity of microalbuminuria（MAU）,hemorheology and biochemical index in young abdominal obesity.Methods：One hundred and forty-six young abdominal obese,143 general obese and 145 healthy volunteers were recruited in this study.The values of MAU,hemorheology and biochemical index were tested and compared in subjects of groups.Results：There were significant differences in the values of MAU,hemorheology and biochemical index between three groups（P 0.01 or P 0.05）.There was a positive correlation between MAU and blood viscosity,plasma viscosity,red cell volume,blood reduced viscosity,erythrocyte aggregation index,erythrocyte rigidity index,triacylglycerol,blood uric acid,urea nitrogen,creatinine and blood sugar（P 0.01 or P 0.05）.But there was a negative correlation between MAU and erythrocyte deformation index and erythrocyte electrophoresis index（P 0.05）.Conclusion：There are abnormal MAU,hemorheology and biochemical indexes with varying degree in young abdominal obesity.MAU is closely related with hemorheology and biochemical index.

关 键 词：肥胖症 腹部 白蛋白尿 血液流变学 红细胞指数 脂类 

分 类 号：R135.2[医药卫生—劳动卫生]