糖尿病肾病患者血液净化治疗影响存活时间的相关因素分析  

Correlative factors affecting survival time in hemodialysis patients with end stage diabetic nephropathy

作　　者：曾春[1] 曾西[1] 张文欣[1] 叶琨[1] 闭闵[1] 龚智峰[1] 彭小梅[1] 

机构地区：[1]广西壮族自治区人民医院泌尿内科,广西血液净化中心,南宁530021

出　　处：《中国临床新医学》2010年第9期814-817,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西卫生厅科研课题(编号:Z2007138)

摘　　要：目的了解糖尿病肾病患者行血液净化治疗影响存活时间的危险因素。方法对广西血液净化中心1998～2008年行血液净化治疗的终末期糖尿病肾病死亡病例按透析时间长短分为A(<3月)、B(3个月～3年)、C(>3年)三组进行回顾性分析。结果 73例死亡患者中,肺水肿及尿毒症症状是较常见的透析指征,心脑血管事件是主要的死亡原因。三组的血浆白蛋白、血红蛋白、甲状旁腺素、内生肌酐清除率等比较差异有统计学意义(P<0.05)。结论影响糖尿病肾病患者长期生存的危险因素是高龄、低蛋白血症、贫血。有效的透析前管理、改善营养状况及贫血有助于提高患者生存时间及质量。Objective To explore factors which influence survival time in hemodialysis patients suffering from diabetic nephrepathy. Methods Death cases over the period from 1999 to 2008 in Guangxi Hemopuriilcation Centre were retrospectively analyzed, which were divided into group A （ 〈 3 months ）, B （between 3 months and 3 years ） and C （ 〉 3 years） respectively according to the treatment duration. Results Hydropneumonia and uremia symptoms normally were dialysis indicators among a total of 73 death patients. Cardiovascular disease and cerebrovascular disease turned out to be primary cause of death. Parameters including serum albumin, hemoglobin, parathyroid hormone and creatinine clearance showed significant difference in 3 groups （P 〈 0. 05）. Conclusion Advanced age, low serum albumin, anemia are factors affecting survival time in hemodialysis patients with diabetic nephropathy. Effective pre-dialysis supervision and amelioration of nutritional condition and anemia will benefit the elongation of life span and improvement of quality of life.

关 键 词：糖尿病肾病 终末期肾病 血液净化 存活因素 

分 类 号：R857.1[医药卫生—航空、航天与航海医学]