中医药辨证治疗抗精神病药所致闭经的临床研究  

Clinical study of the efficacy of traditional Chinese medicine in female patients with amenorrhea caused by antipsychotic drugs

作　　者：石捷[1] 陶建青[1] 梁佳[1] 曾强[1] 尹雪冰[1] 施惠琴[1] 

机构地区：[1]广西壮族自治区人民医院心理康复中心,南宁530022

出　　处：《中国临床新医学》2010年第9期829-831,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的观察中医药辨证治疗抗精神病药物引起药源性闭经的中远期疗效。方法选择服用抗精神病药物导致月经中断达3个月以上的女性精神病患者100例,随机分为两组,分别给予中医药辨证治疗(研究组)与人工周期治疗(对照组),连续观察6个月后评定疗效。结果两组近期疗效相当(P>0.05),但研究组远期疗效优于对照组(P<0.05)。结论中医药辨证治疗抗精神病药物引起的药源性闭经疗效肯定,与人工周期治疗效果相当,但由于中医药的副作用较少,远期疗效好,故能增强患者服药的依从性,减少疾病的复发,提高患者的生活质量。Objective To study the middle and long-term efficacy and side effects of traditional Chinese medicine in the treatment of antipsychotic drugs（AP）-induced amenorrhea in female schizophrenic patients. Methods One hundred female schizophrenic patients with antipsychotic drugs -induced amenorrhea whose menstruation were interrupted more than 3 months were randomly divided into two groups with 50 patients in each group. The treatment group was treated with traditional Chinese medicine for 6 months and the control group was treated with artificial menstrual cycle therapy. Results There were no significant difference between two groups after 3 months treatment （P 〉 0. 05）, the efficacy of study group was better than that of the control group after 6-months of treatment （P 〈 0. 05）. Conclusion Traditional Chinese medicine has better efficacy and fewer side effects for treating amenorrhea caused by antipsychotic drugs in female patients with schizophrenia.

关 键 词：精神分裂症 闭经 副作用 中医药 治疗 

分 类 号：R711.51[医药卫生—妇产科学]