应用自然周期和替代周期进行冻融胚胎移植的临床分析  

Analysis of clinical outcomes of natural and HRT protocols for frozen thawed embryo transfer cycle

作　　者：黄建贞[1] 韩艳[1] 

机构地区：[1]南昌大学第一附属医院辅助生殖科,江西南昌330006

出　　处：《中国妇幼保健》2010年第27期3938-3940,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨两种内膜准备方案冷冻胚胎复苏移植后的妊娠结局。方法:对用于FET子宫内膜准备的两种临床用药方案130个周期进行回顾性分析,比较自然周期与激素替代周期对临床妊娠率、种植率、早期流产率、异位妊娠率的影响是否存在差异。结果:两种用药方案在不孕年龄、不孕年限、妊娠率、种植率、移植胚胎质量上差异均无统计学意义(P>0.05),但在子宫内膜厚度上差异有统计学意义(P<0.01)。FET130个周期中比较妊娠组与非妊娠组在子宫内膜厚度、胚胎移植数上差异均无统计学意义(P>0.05),优质胚胎数差异有统计学意义(P<0.01)。结论:两种用药方案用于FET的子宫内膜准备获得了良好的临床结局,优质胚胎是移植后获得妊娠的关键。Objective：To compare the clinical outcomes of two protocols of frozen-thawed embryo transfer cycle.Methods：A retrospective analysis of the natural and HRT protocols in endometrial preparation for 130 frozen-thawed embryos transfer cycle, pregnancy rate, implantation rate, early abortion rate, ectopic pregnancy rate were compared between the two protocols.Results：There was no significant difference between the two groups with different clinical protocols in age, duration of infertility, pregnancy rate, implantation rate, quality of embryo transfer. However, there was significant difference in endometrial thickness. There was no significant difference in endometrial thickness, number of embryo transfer between the pregnancy and the non-pregnancy. However, the good-quality embryo number was significantly higher in the pregnancy group than that in the non-pregnancy one.Conclusion：Protocols for frozen-thawed embryos transfer all have favorable clinical outcome. The quality of embryo has a significant effect on the clinical pregnancy rate after FET.

关 键 词：冻融胚胎 内膜准备 优质胚胎 妊娠率 种植率 

分 类 号：R711.6[医药卫生—妇产科学]