北京航天总医院ICU感染的病原体分析  

ANALYSIS OF INCIDENCE AND PATHOGENS OF INFECTIONS IN ICU

作　　者：闫冬[1] 赵呈恩 马敏[1] 李德强[1] 董文辉[1] 

机构地区：[1]北京航天总医院ICU,北京100076

出　　处：《现代预防医学》2010年第19期3778-3780,共3页Modern Preventive Medicine

摘　　要：[目的]了解北京航天总医院重症监护病房(ICU)感染的发病率和病原体特点及耐药情况。[方法]收集北京航天总医院ICU2008年1月～2009年12月感染的资料进行回顾性分析。[结果]两年间共ICU患者536例,其中院内感染发病160例,总发病率29.85%(160/536),2008年发病率27.49%(69/251),2009年发病率31.93%(91/285),血行感染发病率4.38%(7/160)。分离病原体160株,革兰阴性杆菌G-(104/160)67.5%,革兰阳性球菌G+(22/160)11.25%,真菌34/160(21.25%)。常见的病原体为真菌11,23(21.25%)鲍曼不动杆菌9,14(14.38%)洋葱伯克氏菌9,12(13.13%)铜绿假单胞菌2,15(10.63%)耐甲氧西林金黄色葡萄球菌8,5(8.13%)醋酸不动杆菌6,2(5%)大肠埃希氏4,2(3.75%)阴沟肠杆菌4,2(3.75%)屎肠球菌3,1(2.5%)嗜麦芽窄食单胞菌1,3(2.5%)。[结论]院内感染发病率上升,病原体以革兰阴性菌为主。常见的致病菌有真菌,鲍曼不动杆菌,洋葱伯克氏菌,铜绿假单胞菌,耐甲氧西林金黄色葡萄球菌,醋酸钙不动杆菌,大肠埃希氏,阴沟肠杆菌,屎肠球菌,嗜麦芽窄食单胞菌。病原体耐药率较高。[Objective] To investigate the incidence,pathogens and antibiotic resistance of infections in ICU of Beijing Aerospace General Hospital. [Methods] The data of incidence and pathogens of infection reported from Jan 2008 to Dec 2009 in ICU of Beijing Aerospace Center Hospital were collected and analyzed. [Results] 536 patients were surveyed and 160 cases with infection were reported. The incidence rate of bloodstream infection was 4.38%,the incidence rate in 2008,2009 were 27.49%,31.93% and total incidence was 29.85%. 160 strains of pathogens had been isolated,among which 34 /160（21.25%） fungi,23 /160（14.38%） Acinetobacter-baumanii,21 /160（13.13%） Burkholderri-acepacia-complex,17 /160（10.63%） P.aeruginosa,13 /160（8.13%） Methicillin resistant staphylococcus aureus（MRSA） ,8 /160（5%） Acinetobacter calcoaceti-cus,6 /160（3.75%） Escherichiacoli,6 /160（3.75%） Enterobactercloacae,4 /160（2.5%） Enterococcus faecalis,4 /160（2.5%） Stenotrophomonas maltphpilia. [Conclusion] The incidence of infection in recent two years is increasing. G-bacteria is the prominent pathogen. The most common pathogens are fungi,Acinetobacter baumanii,Burkholderria cepacia complex,P. aeruginosa,Methicillin resistant staphylococcus aureus（MRSA） ,Acinetobacter calcoaceticus,Escherichiacoli,Enterobacter cloacae,Enterococcus faecalis,Stenotrophomonas maltphpilia. The drug resistance of pathogens is high.

关 键 词：感染 细菌耐药性 病原体 

分 类 号：R372[医药卫生—病原生物学]