瑞芬太尼与芬太尼在胸腔镜手术中的麻醉效果比较  

Effects of reminfentanil combined with propofl in video assisted thoracoscopic surgery

作　　者：张燕[1] 李翃斌[1] 胡佳燕[1] 

机构地区：[1]舟山市人民医院麻醉科,浙江省舟山316000

出　　处：《中国基层医药》2010年第17期2367-2368,2450,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的评价瑞芬太尼复合异丙酚麻醉在胸腔镜手术中的麻醉效果。方法选择在胸腔镜下行肺大泡结扎手术患者40例，ASAⅠ～Ⅱ级，随机分为瑞芬太尼复合异丙酚组（A组）和芬太尼复合异丙酚（B组），每组20例。观察麻醉诱导前（T0）、气管插管前（T1）、气管插管即刻（T2）、气管插管后5min（T，）的BP、HR；记录术毕停药后患者自主呼吸恢复时间、呼之睁眼时间及拔管时间；记录拔管后即刻、30min疼痛视觉模拟评分（VAS）；随访记录术中知晓发生率和术后恶心、呕吐等不良反应。结果A组插管期心血管不良反应显著低于B组（P〈0．05），A组术后自主呼吸恢复时间、呼之睁眼时间及拔管时间明显短于B组（P〈0．05）。两组患者均未出现术中知晓、术后恶心呕吐。结论瑞芬太尼复合异丙酚麻醉明显优于芬太尼复合异丙酚。Objective To evaluate the effects of reminfentanil combined with propofl on patients received video assisted thoraeoscopic surgery. Methods 40 ASA Ⅰ-Ⅱ patients underwent video assisted thoracoscopic surgery were randomly divided into two groups. BP,HR before anesthesia induction（ To ） ,tracheal induction（ T1 ） ,tracheal induction instantly（T2 ）, after five minutes of tracheal induction（T3 ） were observed; The time of breathing recovery withdrawl, and open eye, extubation and instantly of extubation, VAS;to record in the operation and adverse effect of postoperative nausea were analyzed. Results During tracheal induction, hemodynamic and respiratory variables of group R less then group F （P 〈 0.05 ）, after operation group R time of breathing recovery withdrawl, and open eye, extubation is short of group F（P 〈 0. 05）. Two groups was not appear to know in operation, postoperative nausea is not satistieally significant. Conclusion General anesthesia by reminfentanil combined with Propofol on video assisted thoracoscopic surgery was safe and feasible.

关 键 词：瑞芬太尼 异丙酚 胸腔镜手术 

分 类 号：R614[医药卫生—麻醉学]