肝移植受者血脂变化的临床意义  

The Clinical Significance of the Change of Blood Lipids in Patients with Liver Transplantation

作　　者：贾瑛[1] 梁娜[1] 

机构地区：[1]天津市第一中心医院,天津300192

出　　处：《透析与人工器官》2010年第1期12-14,共3页Chinese Journal of Dialysis and Artificial Organs

摘　　要：目的研究肝移植受者术后血脂水平的变化规律及其对受者预后的影响。方法回顾性分析65例肝移植受者的临床资料,动态监测术前及术后1个月、3个月、6个月的三酰甘油(TG)、总胆固醇(TC)。根据术后是否发生高脂血症分为两组,比较术后存活情况。结果肝移植受者术后1个月血脂水平趋于正常,3个月呈增高趋势,6个月又开始下降。高脂血症组术后1年存活率与未并发高脂血症组比较,差异无统计学意义(P>0.05)。结论肝移植术后血脂的变化规律与肝功能的恢复和临床用药治疗密切相关,术后高脂血症不影响受者的1年存活率。Objective To study the change of blood lipids and evaluate its prognostic significance in patients with liver transplantation. Methods The history data of 65 patients who underwent liver transplantation were retrospectively analyzed,triglyceride （TG） and total cholesterol （TC） results were supervised continualy at different time such as 1 month,3 months,6 months,before and after the operation the patients were divided into two groups according to whether developing hyperlipidemia or not,and compare survival rate for one year after the operation. Results The level of blood lipids tended to be normal in 1 month after the operation,for increased after 3 months,and decreased after 6 months. Through comparing the survival rate of two groups in one year after the operation,there had no significant difference （P〉0.05）. Conclusion The changing regulation of blood lipids had a close correlation with the recovery of hepatic function and clinical medicine treatment,hyperlipidemia after the operation had no influence on one-yearsurvival rate ofpatients.

关 键 词：肝移植 血脂 变化规律 存活率 

分 类 号：R657.3[医药卫生—外科学]