谷氨酰胺对早期断奶仔猪血浆、肝和肠中γ-谷氨酰转肽酶活性的影响  

Effect of glutamine supplementation on activities of γ-glutamyl transeptidase in plasma,liver and intestine of early-weaned piglets

作　　者：张军民[1] 高振川[1] 

机构地区：[1]中国农业科学院北京畜牧兽医研究所动物营养学国家重点实验室,北京100193

出　　处：《中国兽医学报》2010年第9期1269-1272,共4页Chinese Journal of Veterinary Science

摘　　要：选用日龄和体质量相近的仔猪40头,公母各半,随机分为试验组和对照组。按等氮等能原则配制日粮,试验组日粮添加1.2%的谷氨酰胺。在35日龄和49日龄采血并每组屠宰5头性别相同的仔猪,取肝脏和肠道,测定仔猪血液、肝脏和肠道中γ-谷氨酰转肽酶(γ-GT)活性。结果,日粮添加谷氨酰胺显著降低35日龄时仔猪血浆中γ-GT活性,49日龄时试验组仔猪血浆中γ-谷氨酰转肽酶活性也低于对照组,但差异不显著;添加谷氨酰胺显著降低35日龄仔猪十二指肠和回肠粘膜和组织中的γ-谷氨酰转肽酶活性,35日龄时空肠的γ-GT活性也明显下降,但与对照组相比差异不显著,49日龄时试验组仔猪不同肠段γ-GT活性都比对照组有所降低,但差异不显著;日粮添加谷氨酰胺对肝蛋白无显著的影响,但显著降低仔猪肝脏的γ-GT活性。日粮添加谷氨酰胺可显著降低早期断奶仔猪血液和肝、肠组织中γ-GT活性。It was to investigate the effect of dietary glutamine supplementation on activities ofγ-GT in plasma,liver and intestine of early-weaned piglets.Forty piglets weaned at the 21 d of age were randomly assigned to two groups with five replicates of four piglets each.The diet in treatment group contained 1.2% glutamine.The diets were calculated to be isonitrogenous and isoenergetic.Five piglets from each dietary treatment were killed at 35 d and 49 d of age.The activities of γ-GT in plasma,liver and intestine of early-weaned piglets were determined.Dietary glutamine supplementation decreased the activities ofγ-GT in plasma at 35 d of age.In treatment group,the activities of γ-GT in duodenum and ileum were significantly lower than those of control at 35 d of age;The activities of γ-GT in jeju- num were lower than those of control,but no significant differences.There was a decreased trend in activities of γ- GT in intestine at 49 d of age in treated piglets.There was no significant change of the liver protein in two group,but dietary glutamine supplementation decreased markedly γ-GT activities in liver.Dietary glutamine supplementation decreased the activities of γ-GT in plasma,liver and intestine of early-weaned piglets.

关 键 词：谷氨酰胺 早期断奶仔猪 Γ-谷氨酰转肽酶 

分 类 号：S856.5[农业科学—临床兽医学]