酸烯酯化合成醋酸叔丁酯的精馏分离过程  

Distillation process for tert-butyl acetate by direct esterification with acetic acid and isobutene

作　　者：施华辉[1] 汤吉海[1] 丁良辉[1] 周峰[1] 崔咪芬[1] 陈献[1] 乔旭[1] 

机构地区：[1]南京工业大学化学化工学院,材料化学工程国家重点实验室,江苏南京210009

出　　处：《南京工业大学学报（自然科学版）》2010年第5期24-27,48,共5页Journal of Nanjing Tech University(Natural Science Edition)

基　　金：国家高新技术研究发展计划(863计划)基金资助项目(2009AA03Z504);江苏省高校自然科学基础研究基金资助项目(08KJB530006);南京工业大学青年教师学术基金资助项目

摘　　要：针对醋酸与异丁烯加成酯化合成叔丁酯的反应液,提出先脱酸后提纯的两塔精馏分离流程,采用AspenP lus软件进行模拟研究.在采用简捷计算方法获得精馏塔初步配置参数的基础上,用严格计算模型对进料位置、回流比的影响进行敏感度分析,得到脱酸塔和提纯塔塔板数、最佳进料位置和回流比分别是25和24、14和20、3和20.在模拟基础上,对精馏过程进行实验研究,实验结果与模拟结果吻合较好,分离得到醋酸叔丁酯的质量分数大于99.50%,为工业应用与放大设计提供了依据.A two-column distillation process for tert-butyl acetate from esterification of acetic acid and isobutene was simulated with Aspen Plus.The configuration parameters were obtained by short-cut calculation model of Aspen Plus,and then the sensitive analysis of the feed stage and the reflux ratio was performed with a rigorous distillation model,and the total stage numbers,optimal feed stage and reflux ratios of deacidification column,and purification column were as 25 and 24,14 and 20,3 and 20,respectively.Experimental research was carried out on the basis of the simulation,and the experimental results and simulation values agreed well.The mass fraction of tert-butyl acetate was over 99.50%,thus it provided a basis for the scale-up design of industrial application.

关 键 词：醋酸叔丁酯 ASPEN PLUS 精馏 模拟 

分 类 号：TQ028.3[化学工程]