鲍曼不动杆菌的感染特征及耐药性分析  

Analysis of infection distribution and drug resistance of Acinetobacter Baumannii

作　　者：王悦妮[1] 

机构地区：[1]沈阳医学院奉天医院检验科,辽宁沈阳110024

出　　处：《中国民康医学》2010年第19期2443-2445,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:了解我院鲍曼不动杆菌的感染分布与耐药情况,为临床治疗提供依据。方法:对住院患者送检样本中培养分离出的71株鲍曼不动杆菌的感染分布与耐药情况进行分析。采用稀释法进行药物敏感试验,结果按CLSI标准判定。结果:鲍曼不动杆菌主要分布在重症监护病房(ICU)、胸外科和呼吸科,主要来自痰标本(95.77%),对亚胺培南的耐药率最低(31.0%),其次为头孢哌酮/舒巴坦(39.4%),对其他20种抗菌药物的耐药率均较高。结论:鲍曼不动杆菌主要引起呼吸道感染,对现有多种抗菌药物耐药严重,提示临床医生必须对该菌所致感染予以高度重视,关注易感人群,加强对该菌的监测,合理使用抗生素,以提高疗效和减缓耐药株的产生。Objective：To investigate the clinical distribution and drug resistance of Acinetobacter baumannii in order to offer basis for the clinical therapeutics.Methods：Analyze the infection distribution and drug resistance of 71 samples of Acinetobacter baumannii that were isolated from various kinds of specimens from inpatients.The drug sensitivity test was done by means of dilution,and then the results were assessed with CLSI（Clinical and Laboratory Standards Institute）.Results： Acinetobacter baumannii samples were mainly distributed in ICU ward,Brain Surgery department and Respiration department.The highest positive rate of Acinetobacter baumannii was in sputum（95.77%）.The resistance rates to Imipenem（31.0%） were the lowest,and to Cefoperazone-Sulbactam（39.4%） came to be next.Acinetobacter baumannii were high resistant to other 20 tested antibiotics.Conclusions： Acinetobacter baumannii is a common pathogen of respiratory tract infection,which has a high resistance rate to the current clinical antibacterial agents.Consequently,clinical doctors should attach more importance to the infection resulted from Acinetobacter Baumannii,pay more attention to inpatients easily infected,monitor it more frequently,and use antibiotics more carefully in order to increase the positive effect and reduce drug resistance.

关 键 词：鲍曼不动杆菌 医院感染 临床分布 耐药性 

分 类 号：R446.5[医药卫生—诊断学]