辽宁省肾综合征出血热流行特征分析  

Epidemiology of hemorrhagic fever with renal syndrome in Liaoning

作　　者：姚文清[1] 孙英伟[1] 刘敏[1] 韩仰欢[1] 李鑫[1] 

机构地区：[1]辽宁省疾病预防控制中心,辽宁沈阳110005

出　　处：《疾病监测》2010年第9期724-726,共3页Disease Surveillance

基　　金：辽宁省科技厅计划项目(No.2007403016)~~

摘　　要：目的探索辽宁省肾综合征出血热(HFRS)的流行规律,为制定防制策略提供科学依据。方法采用描述流行病学方法分析HFRS疫情,开展宿主动物监测,检测鼠密度和鼠带病毒率。结果 1962-2008年辽宁省累计报告HFRS病例53525例,年平均发病率为2.85/10万,死亡1042例,病死率为1.95%。家鼠型疫区不断扩大,混合型疫区逐年增加,病例地区分布由20世纪80年代的仅4个地区发展为现今病例覆盖全省14个市90%的县(区)。每年3-6月和11月至次年1月有2个流行高峰。年龄发病以15～60岁人群为主,职业以农民为主,约占70%。结论自21世纪初辽宁省HFRS疫情呈快速上升趋势,2005年以后由于在重点地区和人群中疫苗的大规模应用,疫情得到了有效遏制。Objective To understand the epidemiological features of hemorrhagic fever with renal syndrome （HFRS） in Liaoning and provide evidence for the prevention and control of HFRS. Methods Descriptive epidemiological analysis of HFRS epidemic was conducted and host animal surveillance was carried out to detect rat density and virus carrying rate. Results A total of 53 525 HFRS cases were reported from 1962 to 2008,including 1042 deaths. The average annual incidence was 2.85/lakh and case fatality was 1.95%. Both rattus type endemic area and mixed type endemic area increased gradually. The cases were distributed in only 4 areas in 1980s,but now in 90% of the counties （district） in 14 municipalities in the province. The incidence peaked during March-June and November-January. The cases were aged 15-60 years and most of them were farmers （70%）. Conclusion The incidence of HFRS once increased rapidly at beginning of this century,but the epidemic had been under effective control since 2005 when mass vaccination among the population in risk areas started.

关 键 词：肾综合征出血热 流行特征 宿主动物 

分 类 号：R512.8[医药卫生—内科学]