6株嗜水气单胞菌的毒力因子及其对小鼠的致死性  

Virulent Factors of 6 Strains of Aeromonas hydrophila and Their Pathogenicity to Mouse

作　　者：凌红丽[1] 陆承平[1] 陈怀青[1] 马向东[1] 

机构地区：[1]南京农业大学动物医学院

出　　处：《中国兽医学报》1999年第3期255-257,共3页Chinese Journal of Veterinary Science

基　　金：国家"九五"攻关项目

摘　　要：根据嗜水气单胞菌毒素、蛋白酶及Ｓ蛋白３种毒力因子的检测结果，从６６株嗜水气单胞菌中选出３种毒力因子分布情况各异的有代表性的６个菌株。分别用含菌量均为１０８ＣＦＵ／ｍＬ的６株嗜水气单胞菌肉汤培养物注射小鼠，结果，毒素、蛋白酶及Ｓ蛋白均有的菌株以及具有前两者而无Ｓ蛋白的菌株对小鼠的致死率均达１００％；仅有蛋白酶的菌株对小鼠致死率达６０％；而只有Ｓ蛋白的，或既有毒素又有Ｓ蛋白的，或３种毒力因子均无的菌株对小鼠无致死性。After detection of toxin, protease and Slayer from 66 Aeromonas hydrophila (A.hydrophila) strains, six strains with different virulent factors were tested their pathogenicity to mouse. The results demonstrated that the different strains were able to produce different virulent factors and they had different lethal rates. Both strains which were with toxin, protease and Slayer or with toxin and protease but no Slayer, killed 100% mice. The lethality of the strain only with protease reached 60%. The strains with toxin and Slayer but without protease, or only with Slayer, or of nothing in the three virulent factors had no lethality.

关 键 词：嗜水气单胞菌 毒力因子 小鼠 致死性 

分 类 号：S852.61[农业科学—基础兽医学]