甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良的疗效观察  

Efficacy Observation of Reboxetine Mesylate Combined with Cisapride in the Treatment of Functional Dyspepsia

作　　者：黄新刚[1] 

机构地区：[1]胜利油田中心医院药剂科,东营市370502

出　　处：《中国药房》2010年第38期3612-3613,共2页China Pharmacy

摘　　要：目的:观察甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良的疗效。方法:146例功能性消化不良患者随机分成2组。治疗组76例,给予甲磺酸瑞波西汀胶囊联合西沙必利片治疗;对照组70例,给予西沙必利片治疗。疗程均为4周。结果:治疗组与对照组的总有效率分别为84.21%、61.43%,差异有统计学意义(P<0.05);治疗结束8周后随防,治疗组与对照组的复发率分别为12.50%、30.23%,差异有统计学意义(P<0.05)。结论:甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良疗效好。OBJECTIVE：To evalvuate the clinical efficacy of reboxetine mesylate combined with cisapride in the treatment of functional dyspepsia（FD）.METHODS：146 patients with FD were randomly divided into 2 groups.Treatment group received Reboxetine mesylate capsules and Cisapride tablets for 4 weeks（n=76）.Control group received Cisapride tablets for 4 weeks（n=70）.RESULTS：The total effective rates were 84.21% for treatment group and 61.43% for control group,significant difference was found between 2 groups（P0.05）.Following up after 8 weeks of treatment,the relapse rates were 12.50% for treatment group and 30.23% for control group,significant difference was found between 2 groups（P0.05）.CONCLUSION：Reboxetine mesylate combined with cisapride has satisfactory efficacy in the treatment of functional dyspepsia.

关 键 词：功能性消化不良 甲磺酸瑞波西汀 西沙必利 

分 类 号：R969.4[医药卫生—药理学] R975[医药卫生—药学]