我院394例药品不良反应报告分析  

Analysis of 394 ADR Reports in Our Hospital

作　　者：刘心慧[1] 

机构地区：[1]江苏大学附属医院,镇江市212001

出　　处：《中国药房》2010年第38期3622-3624,共3页China Pharmacy

摘　　要：目的:了解我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2008年1月～2009年7月收集到的394例ADR报告进行统计、分析。结果:≤10岁人群发生ADR的比例最高,有100例(占25.38%);静脉滴注引起的ADR有283例(占71.83%);引起ADR的药品共15类97种,抗菌药物居首位,有246例(占62.44%);ADR类型主要表现为皮肤及其附件损害,有236例(占59.90%);严重ADR30例,占7.61%,其中以肝功能异常发生率最高。结论:临床重视和加强ADR监测工作,能有效地减少ADR的发生。OBJECTIVE：To probe into the regularity and characteristics of ADR in our hospital.METHODS：394 ADR cases collected from our hospital between Jan.2008 and Jul.2009 were analyzed statistically.RESULTS：The incidence of ADR cases were the highest in patients under 10 years old（n=100,25.38%）.283 ADR cases were induced by intravenous administration（71.83%）.15 categories（97 kinds）of drugs were involved in ADR.246 ADR cases were caused by antibiotic（62.44%）.Main clinical manifestation were lesion of skin and its appendants（n=236,59.90%）.There were 30 severe ADR cases,accounting for 7.61%,in which the incidence of abnormal liver function was the highest.CONCLUSION：Great importance should be attached to ADR monitoring to reduce the incidence of ADR.

关 键 词：药品不良反应 报告 分析 监测 合理用药 

分 类 号：R969.3[医药卫生—药理学]