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机构地区:[1]华中科技大学同济医学院附属同济医院生殖中心,湖北武汉430030
出 处:《中国实用妇科与产科杂志》2010年第10期748-750,共3页Chinese Journal of Practical Gynecology and Obstetrics
摘 要:黄体功能不全是指排卵后黄体分泌孕酮不足或黄体过早萎缩致使子宫内膜发育延迟,临床以内膜发育与孕卵发育不同步为主要特征,与不孕或流产密切相关。目前尚无明确的诊断方法,多以基础体温测定、子宫内膜活检以及黄体中期孕酮水平的测定相结合诊断。病因多样,多与影响卵泡发育或干扰LH分泌的疾病相关。临床上以促卵泡发育、应用黄体酮等对症支持治疗为主。Luteal phase defect (LPD) is implicated in infertility and recurrent abortion. The various diagnostic methods including basal body temperature, endometrial biopsy, and measurement of progesterone are used to evaluate the corpus luteum function, and usually the methods combined together to diagnosis the LPD. The etiology is multifactorial and usually is related to the hypothalamic-pituitary factors influencing the folliculogenesis and the LH surge, rather than to ovarian factors. Once diagnosed, the treatment options are empiric and those treatment including simulating follicles growth and applying progesterone to support are recommended.
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